July 2008

J Psychiatry Neurosci 2008;33(4)


Advances in neurobiology, assessment and treatment of female-specific mood disorders
M. Steiner

Review papers

Premenstrual dysphoric disorder: burden of illness and treatment update
T. Pearlstein, M. Steiner

Perinatal depression: treatment options and dilemmas
T. Pearlstein

Sex steroid–related candidate genes in psychiatric disorders
L. Westberg, E. Eriksson

Reproductive hormone sensitivity and risk for depression across the female life cycle: A continuum of vulnerability?
C.N. Soares, B. Zitek


Short telomeres in patients with chronic schizophrenia who show a poor response to treatment

Research Paper

A new, female-specific irritability rating scale
L. Born, G. Koren, E. Lin, M. Steiner

CCNP News and Views

Canadian College of Neuropsychopharmacology 2008 Award Winners

Psychopharmacology for the Clinician

Treating depression during pregnancy
M. Steiner

September 2008

J Psychiatry Neurosci 2008;33(5)


The neurobiology of human social behaviour: an important but neglected topic
S.N. Young

Review papers

Diabetes mellitus during pregnancy and increased risk of schizophrenia in offspring: a review of the evidence and putative mechanisms
R.J. Van Lieshout, L.P. Voruganti

Provocation of obsessive–compulsive symptoms: a quantitative voxel-based meta-analysis of functional neuroimaging studies
J.-Y. Rotge, D. Guehl, B. Dilharreguy, E. Cuny, J. Tignol, B. Bioulac, M. Allard, P. Burbaud, B. Aouizerate

Research Papers

The neural networks of inhibitory control in posttraumatic stress disorder
E. Falconer, R. Bryant, K.L. Felmingham, A.H. Kemp, E. Gordon, A. Peduto, G. Olivieri, L.M. Williams

Effect of hippocampal and amygdala volumes on clinical outcomes in major depression: a 3-year prospective magnetic resonance imaging study
T. Frodl, M. Jäger, I. Smajstrlova, C. Born, R. Bottlender, T. Palladino, M. Reiser, H.-J. Möller, E.M. Meisenzahl

Cerebral ventricular volume and temperamental difficulties in infancy. The Generation R Study
S.J. Roza, P.P. Govaert, M.H. Lequin, V.W.V. Jaddoe, H.A. Moll, E.A.P. Steegers, A. Hofman, F.C. Verhulst, H. Tiemeier

Microstructural thalamic changes in schizophrenia: a combined anatomic and diffusion weighted magnetic resonance imaging study
N. Agarwal, G. Rambaldelli, C. Perlini, N. Dusi, O. Kitis, M. Bellani, R. Cerini, M. Isola, A. Versace, M. Balestrieri, A. Gasparini, R. Pozzi Mucelli, M. Tansella, P. Brambilla

Brief Reports

BDNF protein levels are decreased in transformed lymphoblasts from lithium-responsive patients with bipolar disorder
M. Tseng, M. Alda, L. Xu, X. Sun, J.-F. Wang, P. Grof, G. Turecki, G. Rouleau, T.L. Young

Psychopharmacology for the Clinician

Smoking cessation: the psychiatrist’s role
N.J. Delva

May 2009

J Psychiatry Neurosci 2009;34(3)

Editorial • Éditorial

Moving past the “neuroncentric” perspective: a role for glia in neuropsychiatric disorders
A.Y. Lai, K.S. Dhami, K.G. Todd

Research Papers • Articles de recherche

Predictors of nonresponse to cognitive behavioural therapy or venlafaxine using glucose metabolism in major depressive disorder
J.Z. Konarski, S.H. Kennedy, Z.V. Segal, M.A. Lau, P.J. Bieling, R.S. McIntyre, H.S. Mayberg

Neuregulin 1 genetic variation and anterior cingulum integrity in patients with schizophrenia and healthy controls
F. Wang, T. Jiang, Z. Sun, S. Teng, X. Luo, Z. Zhu, Y. Zang, H. Zhang, W. Yue, M. Qu, T. Lu, N. Hong, H. Huang, H.P. Blumberg, D. Zhang

Alterations in default network connectivity in posttraumatic stress disorder related to early-life trauma
R.L. Bluhm, P.C. Williamson, E.A. Osuch, P.A. Frewen, T.K. Stevens, K. Boksman, R.W.J. Neufeld, J. Théberge, R.A. Lanius

Positive association of the pericentrin (PCNT) gene with major depressive disorder in the Japanese population
S. Numata, J. Iga, M. Nakataki, S. Tayoshi, T. Tanahashi, M. Itakura, S. Ueno, T. Ohmori

Positive association between the PDLIM5 gene and bipolar disorder in the Chinese Han population
T. Zhao, Y. Liu, P. Wang, S. Li, D. Zhou, D. Zhang, Z. Chen, T. Wang, H. Xu, G. Feng, L. He, L. Yu

Influence of androgen receptor repeat polymorphisms on personality traits in men
L. Westberg, S. Henningsson, M. Landén, K. Annerbrink, J. Melke, S. Nilsson, R. Rosmond, G. Holm, H. Anckarsäter, E. Eriksson

Emotional learning during dissociative states in borderline personality disorder
U.W. Ebner-Priemer, J. Mauchnik, N. Kleindienst, C. Schmahl, M. Peper, M.Z. Rosenthal, H. Flor, M. Bohus

Effects of sustained serotonin reuptake inhibition on the firing of dopamine neurons in the rat ventral tegmental area
E. Dremencov, M. El Mansari, P. Blier

Commentary • Commentaire

Effects of gut microbiota on the brain: implications for psychiatry
K.-A. Neufeld, J.A. Foster

Brief Report / Rapport sommaire

Dimethylated lysine 9 of histone 3 is elevated in schizophrenia and exhibits a divergent response to histone deacetylase inhibitors in lymphocyte cultures
D.P. Gavin, C. Rosen, K. Chase, D.R. Grayson, N. Tun, R.P. Sharma

Psychopharmacology for the Clinician • Psychopharmacologie pratique

Treatment of comorbid tobacco use in people with serious mental illness
K. Lising-Enriquez, T.P. George

November 2008

J Psychiatry Neurosci 2008;33(6)


What is the best treatment for bipolar depression?
L.T. Young

Review paper

The mediodorsal thalamic nucleus and schizophrenia
R. Alelú-Paz, J.M. Giménez-Amaya

Research Papers

Serotonin2A receptor binding potential in people with aggressive and violent behaviour
J.H. Meyer, A.A. Wilson, P. Rusjan, M. Clark, S. Houle, S. Woodside, J. Arrowood, K. Martin, M. Colleton

Hippocampus and amygdala morphology in adults with attention-deficit hyperactivity disorder
E. Perlov, A. Philipsen, L. Tebartz van Elst, D. Ebert, J. Henning, S. Maier, E. Bubl, B. Hesslinger

Effects of mood stabilizers on DNA damage in an animal model of mania
A.C. Andreazza, M. Kauer-Sant’Anna, B.N. Frey, L. Stertz, C. Zanotto, L. Ribeiro, K. Giasson, S.S. Valvassori, G.Z. Réus, M. Salvador, J. Quevedo, C.A. Gonçalves, F. Kapczinski

Alterations of white matter integrity in adults with major depressive disorder: a magnetic resonance imaging study
K. Zou, X. Huang, T. Li, Q. Gong, Z. Li, L. Ou-yang, W. Deng, Q. Chen, C. Li, Y. Ding, X. Sun

A comparison of affected and unaffected relatives of patients with bipolar disorder using proton magnetic resonance spectroscopy
T. Hajek, D. Bernier, C. Slaney, L. Propper, M. Schmidt, N. Carrey, G. MacQueen, A. Duffy, M. Alda

Serotonin1B heteroreceptor activation induces an antidepressant-like effect in mice with an alteration of the serotonergic system
F. Chenu, D.J.P. David, I. Leroux-Nicollet, E. Le Maître, A.M. Gardier, M. Bourin

Psychopharmacology for the Clinician

Implementing antiobesity treatment in a patient with a mood disorder
V.H. Taylor

July 2009

J Psychiatry Neurosci 2009;34(4)


On the neurobiology of hallucinations
P. Boksa

Research Papers

3-Nitrotyrosine and glutathione antioxidant system in patients in the early and late stages of bipolar disorder
A.C. Andreazza, F. Kapczinski, M. Kauer-Sant’Anna, J.C. Walz, D.J. Bond, C.A. Gonçalves, L.T. Young, L.N. Yatham

Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation
S. Manta, J. Dong, G. Debonnel, P. Blier

Alcohol dependence–related increase of glial cell density in the anterior cingulate cortex of suicide completers
C. Hercher, M. Parent, C. Flores, L. Canetti, G. Turecki, N. Mechawar

Hippocampus and amygdala volumes in patients with borderline personality disorder with or without posttraumatic stress disorder
C. Schmahl, K. Berne, A. Krause, N. Kleindienst, G. Valerius, E. Vermetten, M. Bohus

Amygdala and insula response to emotional images in patients with generalized social anxiety disorder
S.G. Shah, H. Klumpp, M. Angstadt, P.J. Nathan, K.L. Phan

Emotion-elicited gamma synchrony in patients with first-episode schizophrenia: a neural correlate of social cognition outcomes
L.M. Williams, T.J. Whitford, M. Nagy, G. Flynn, A.W.F. Harris, S.M. Silverstein, E. Gordon

Increased whole-body auditory startle reflex and autonomic reactivity in children with anxiety disorders
M.J. Bakker, M.A.J. Tijssen, J.N. van der Meer, J.H.T.M. Koelman, F. Boer

Serum brain-derived neurotrophic factor and peripheral indicators of the serotonin system in underweight and weight-recovered adolescent girls and women with anorexia nervosa
S. Ehrlich, H. Salbach-Andrae, S. Eckart, J.V. Merle, R. Burghardt, E. Pfeiffer, L. Franke, R. Uebelhack, U. Lehmkuhl, R. Hellweg

Psychopharmacology for the Clinician

Bariatric surgery in patients with bipolar disorder: an emerging issue
V.H. Taylor, M. Misra

January 2010

J Psychiatry Neurosci 2010;35(1)


Bioanalytical inaccuracy: a threat to the integrity and efficiency of research
S.N. Young, G.M. Anderson

Research Papers

The contribution of hypersalience to the “jumping to conclusions” bias associated with delusions in schizophrenia
W.J. Speechley, J.C. Whitman, T.S. Woodward

Doxycycline inhibits proinflammatory cytokines but not acute cerebral cytogenesis after hypoxia–ischemia in neonatal rats
L.L. Jantzie, K.G. Todd

Hippocampal subdivision and amygdalar volumes in patients in an at-risk mental state for schizophrenia
H. Witthaus, U. Mendes, M. Brüne, S. Özgürdal, G. Bohner, Y. Gudlowski, P. Kalus, N. Andreasen, A. Heinz, R. Klingebiel, G. Juckel

Differential patterns of initial and sustained responses in amygdala and cortical regions to emotional stimuli in schizophrenia patients and healthy participants
P. Salgado-Pineda, E. Fakra, P. Delaveau, A.R. Hariri, O. Blin

Social cognition mediates illness-related and cognitive influences on social function in patients with schizophrenia-spectrum disorders
J. Addington, T.A. Girard, B.K. Christensen, D. Addington

Brief Reports

Structural abnormality of the substantia nigra in children with attention-deficit hyperactivity disorder
M. Romanos, D.Weise, M. Schliesser, M. Schecklmann, J. Löffler, A. Warnke, M. Gerlach, J. Classen, C. Mehler-Wex

Circulating plasmalogen levels and Alzheimer Disease Assessment Scale–Cognitive scores in Alzheimer patients
P.L. Wood, R. Mankidy, S. Ritchie, D. Heath, J.A. Wood, J. Flax, D.B. Goodenowe

CCNP News and Views

In memoriam: Dr. Samarthji Lal

Psychopharmacology for the Clinician

Treatment of bipolar disorder with comorbid migraine
A. Ortiz, M. Alda

July 2010

J Psychiatry Neurosci 2010;35(4)


The well of novel antidepressants: running dry
P. Blier

Review Paper

Continuing the search for the engram: examining the mechanism of fear memories
S.A. Josselyn

Research Papers

Brain volumes in psychotic youth with schizophrenia and mood disorders
M. El-Sayed, R.G. Steen, M.D. Poe, T.C. Bethea, G. Gerig, J. Lieberman, L. Sikich

Clinical correlations of grey matter reductions in the caudate nucleus of adults with attention deficit hyperactivity disorder
L.G. Almeida Montes, J. Ricardo-Garcell, L. Barajas De La Torre, H. Prado Alcántara, R.B. Martínez García, A. Fernández-Bouzas, D. Ávila Acosta

Differential effects of serotonergic and noradrenergic antidepressants on brain activity during a cognitive control task and neurofunctional prediction of treatment outcome in patients with depression
G. Wagner, K. Koch, C. Schachtzabel, T. Sobanski, J.R. Reichenbach, H. Sauer, R.G.M Schlösser

Switching between executive and default mode networks in posttraumatic stress disorder: alterations in functional connectivity
J.K. Daniels, A.C. McFarlane, R.L. Bluhm, K.A. Moores, C.R. Clark, M.E. Shaw, P.C. Williamson, M. Densmore, R.A. Lanius

Emotion brain alterations in anorexia nervosa: a candidate biological marker and implications for treatment
A. Hatch, S. Madden, M.R. Kohn, S. Clarke, S. Touyz, E. Gordon, L.M. Williams

Psychopharmacology for the Clinician

Options for the treatment of febrile catatonia
G. Northoff



March 2010

J Psychiatry Neurosci 2010;35(2)


Gamma oscillations and schizophrenia
S. Williams, P. Boksa

Review Paper

Does neuroimaging research examining the pathophysiology of posttraumatic stress disorder require medication-free patients?
R.A. Lanius, C.R. Brewin, J.D. Bremner, J.K. Daniels, M.J. Friedman, I. Liberzon, A. McFarlane, P.P. Schnurr, L. Shin, M. Stein, E. Vermetten

CCNP News and Views

Canadian College of Neuropsychopharmacology 2009 Award Winners

Research Papers

Correlation between errors on the Wisconsin Card Sorting Test and the availability of striatal dopamine transporters in healthy volunteers
P.C. Hsieh, T.L. Yeh, I.H. Lee, H.C. Huang, P.S. Chen, Y.K. Yang, N.T. Chiu, R.B. Lu, M.-H. Liao

Hippocampal and caudate volume reductions in antipsychotic-naive first-episode schizophrenia
B.H. Ebdrup, B. Glenthøj, H. Rasmussen, B. Aggernaes, A.R. Langkilde, O.B. Paulson, H. Lublin, A. Skimminge, W. Baaré

Neural circuitry of emotional face processing in autism spectrum disorders
C.S. Monk, S.-J. Weng, J.L. Wiggins, N. Kurapati, H.M.C. Louro, M. Carrasco, J. Maslowsky, S. Risi, C. Lord

Longitudinal study of carbon monoxide intoxication by diffusion tensor imaging with neuropsychiatric correlation
C.-C. Chang, W.-N. Chang, C.-C. Lui, J.-J. Wang, C.-F. Chen, Y.-C. Lee, S.-S. Chen, Y.-T. Lin, C.-W. Huang, C. Chen

Brief Report

Reduced amygdalar and hippocampal size in adults with generalized social phobia
E. Irle, M. Ruhleder, C. Lange, U. Seidler-Brandler, S. Salzer, P. Dechent, G. Weniger, E. Leibing, F. Leichsenring

Psychopharmacology for the Clinician

Tryptophan for refractory bipolar spectrum disorder and sleep-phase delay
R.G. Cooke, R.D. Levitan

May 2010

J Psychiatry Neurosci 2010;35(3)


Clozapine: a distinct, poorly understood and under-used molecule
R. Joober, P. Boksa

Research Papers

Medial prefrontal cortex activity during memory encoding of pictures and its relation to symptomatic improvement after citalopram treatment in patients with major depression
M. Roy, P.-O. Harvey, M.T. Berlim, F. Mamdani, M.-M. Beaulieu, G. Turecki, M. Lepage

Neural correlates of viewing photographs of one’s own body and another woman’s body in anorexia and bulimia nervosa: an fMRI study
S. Vocks, M. Busch, D. Grönemeyer, D. Schulte, S. Herpertz, B. Suchan

Pain sensitivity and neural processing during dissociative states in patients with borderline personality disorder with and without comorbid posttraumatic stress disorder: a pilot study
P. Ludäscher, G. Valerius, C. Stiglmayr, J. Mauchnik, R.A. Lanius, M. Bohus, C. Schmahl

Multisensory integration of emotionally valenced olfactory–visual information in patients with schizophrenia and healthy controls
J. Seubert, J. Loughead, T. Kellermann, F. Boers, C.M. Brensinger, U. Habel

Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder
S.K. Olsson, M. Samuelsson, P. Saetre, L. Lindström, E.G. Jönsson, C. Nordin, G. Engberg, S. Erhardt, M. Landén

CCNP News and Views

Canadian College of Neuropsychopharmacology 2010 Award Winners

Letters to the Editor

Hippocampal volume reduction specific for later transition to psychosis or substance-associated effects?
Stefan Borgwardt, Renata Smieskova, Kerstin Bendfeldt, Eva Bühlmann, Gregor Berger, Jacqueline Aston, Ute Gschwandtner, Marlon Pflueger, Rolf-Dieter Stieglitz, Anita Riecher-Rössler, Ernst-Wilhelm Radue, MD, PhD

Hippocampal alterations in ultra-high risk patients are independent from medication and cannabis use
Henning Witthaus, Martin Brüne, Georg Juckel

Psychopharmacology for the Clinician

The overdiagnosis of bipolar disorder
I. Iordache, N.C. Low

September 2010

J Psychiatry Neurosci 2010;35(5)


Will there be a role for neuroimaging in clinical psychiatry?
G.M. MacQueen

Research Papers

Oxidative damage to RNA but not DNA in the hippocampus of patients with major mental illness
Y. Che, J.-F. Wang, L. Shao, L.T. Young

Osteoprotegerin levels in patients with severe mental disorders
S. Hope, I. Melle, P. Aukrust, I. Agartz, S. Lorentzen, N.E. Steen, S. Djurovic, T. Ueland, O.A. Andreassen

Orbitofrontal volume reductions during emotion recognition in patients with major depression
J. Scheuerecker, E.M. Meisenzahl, N. Koutsouleris, M. Roesner, V. Schöpf, J. Linn, M. Wiesmann, H. Brückmann, H.- J. Möller, T. Frodl

Neural correlates of set-shifting: decomposing executive functions in schizophrenia
A. Wilmsmeier, P. Ohrmann, T. Suslow, A. Siegmund, K. Koelkebeck, M. Rothermundt, H. Kugel, V. Arolt, J. Bauer, A. Pedersen

Regional differences in cerebral perfusion associated with the α-2A-adrenergic receptor genotypes in attention deficit hyperactivity disorder
B.-N. Kim, J.-W. Kim, H. Kang, S.-C. Cho, M.-S. Shin, H.-J. Yoo, S.-B. Hong, D.S. Lee

Structural changes in the hippocampus in major depressive disorder: contributions of disease and treatment
N.V. Malykhin, R. Carter, P. Seres, N.J. Coupland

Psychopharmacology for the Clinician

Autism spectrum disorders, schizo phrenia and diagnostic confusion
M.R. Woodbury-Smith, K. Boyd, P. Szatmari

March 2009

J Psychiatry Neurosci 2009;34(2)


NeuroAIDS: a watershed for mental health and nervous system disorders
J.A. McCombe, F. Noorbakhsh, C. Buchholz, M. Trew, C. Power

Review paper

Candidate genes and neuropsychological phenotypes in children with ADHD: review of association studies
O. Kebir, K. Tabbane, S. Sengupta, R. Joober

Research Papers

2007 CCNP Young Investigator Award paper: Relation between emotional face memory and social anhedonia in schizophrenia
P.-O. Harvey, M. Bodnar, K. Sergerie, J. Armony, M. Lepage

Latent deleterious effects of binge drinking over a short period of time revealed only by electrophysiological measures
P. Maurage, M. Pesenti, P. Philippot, F. Joassin, S. Campanella

Acute effects of repetitive transcranial magnetic stimulation on attentional control are related to antidepressant outcomes
M.-A. Vanderhasselt, R. De Raedt, L. Leyman, C. Baeken

Cortical folding in patients with bipolar disorder or unipolar depression
J. Penttilä, M.-L. Paillère-Martinot, J.-L. Martinot, D. Ringuenet, M. Wessa, J. Houenou, T. Gallarda, F. Bellivier, A. Galinowski, P. Bruguière, F. Pinabel, M. Leboyer, J.-P. Olié, E. Duchesnay, E. Artiges, J.-F. Mangin, A. Cachia

Association of total tau and phosphorylated tau 181 protein levels in cerebrospinal fluid with cerebral atrophy in mild cognitive impairment and Alzheimer disease
P.A. Thomann, E. Kaiser, P. Schönknecht, J. Pantel, M. Essig, J. Schröder


Glutamate and dopamine components in schizophrenia
P. Seeman

Psychopharmacology for the Clinician

Do serum lipids predict response to clozapine treatment?
R.M. Procyshyn, W.G. Honer, A.M. Barr

January 2009

J Psychiatry Neurosci 2009;34(1)


Has the time come for clinical trials on the antidepressant effect of vitamin D?
S.N. Young

Review Paper

2008 CCNP Heinz Lehmann Award paper: Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder
H. Anisman

Research Papers

Neural synchrony in patients with a first episode of schizophrenia: tracking relations with grey matter and symptom profile
L.M. Williams, T.J. Whitford, E. Gordon, L. Gomes, K.J. Brown, A.W.F. Harris

Genotype over diagnosis in amygdala responsiveness: affective processing in social anxiety disorder
T. Furmark, S. Henningsson, L. Appel, F. Åhs, C. Linnman, A. Pissiota, V. Faria, L. Oreland, M. Bani, E. Merlo Pich, E. Eriksson, M. Fredrikson

A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder
M.C. McKinnon, K. Yucel, A. Nazarov, G.M. MacQueen


A new wave in the genetics of psychiatric disorders: the copy number variant tsunami
R. Joober, P. Boksa

Brief Report

High-frequency repetitive transcranial magnetic stimulation to the cerebellum and implicit processing of happy facial expressions
D.J.L.G. Schutter, D. Enter, S.S. Hoppenbrouwers

CCNP News and Views

The 31st Annual Meeting of the Canadian College of Neuropsychopharmacology
C. Flores, L. Zawertailo, J. Meyer, M. Leyton


2008 Reviewers

Psychopharmacology for the Clinician

Optimal use of antidepressants: When to act?
P. Blier

November 2010

J Psychiatry Neurosci 2010;35(6)


Epigenetics in mental illness: Hope or hype?
P.R. Albert

Research Papers

Perceived early-life maternal care and the cortisol response to repeated psychosocial stress
V. Engert, S.I. Efanov, K. Dedovic, A. Duchesne, A. Dagher, J.C. Pruessner

Impact of cognitive performance on the reproducibility of fMRI activation in schizophrenia
O. Maïza, B. Mazoyer, P.-Y. Hervé, A. Razafimandimby, S. Dollfus, N. Tzourio-Mazoyer

Neural responses to emotional and neutral facial expressions in chronically violent men
D.A. Pardini, M. Phillips

Dysregulation of the sympathetic nervous system, hypothalamic–pituitary–adrenal axis and executive function in individuals at risk for suicide
A. McGirr, G. Diaconu, M.T. Berlim, J.C. Pruessner, R. Sablé, S. Cabot, G. Turecki

Brief Report

White-matter abnormalities in adolescents with long-term inhalant and cannabis use: a diffusion magnetic resonance imaging study
M. Yücel, A. Zalesky, M.J. Takagi, E. Bora, A. Fornito, M. Ditchfield, G.F. Egan, C. Pantelis, D.I. Lubman

Psychopharmacology for the Clinician

Is there a role for estrogen in treating depression during menopause?
C.N. Soares, B.N. Frey

January 2011

J Psychiatry Neurosci 2011;36(1)


Possible directions for the discovery of new antidepressant treatments
S.N. Young

Research Papers

Effects of trauma-related cues on pain processing in posttraumatic stress disorder: an fMRI investigation
M.J.S. Mickleborough, J.K. Daniels, N.J. Coupland, R. Kao, P.C. Williamson, U.F. Lanius, K. Hegadoren, A. Schore, M. Densmore, T. Stevens, R.A. Lanius

Structural MRI correlates for vulnerability and resilience to major depressive disorder
F. Amico, E. Meisenzahl, N. Koutsouleris, M. Reiser, H.-J. Möller, T. Frodl

Abnormal small-world architecture of top–down control networks in obsessive–compulsive disorder
T. Zhang, J. Wang, Y. Yang, Q. Wu, B. Li, L. Chen, Q. Yue, H. Tang, C. Yan, S. Lui, X. Huang, R.C.K. Chan, Y. Zang, Y. He, Q. Gong

Pervasive microstructural abnormalities in autism: a DTI study
W.B. Groen, J.K. Buitelaar, R.J. van der Gaag, M.P. Zwiers

White matter microstructure in patients with obsessive–compulsive disorder
E. Bora, B.J. Harrison, A. Fornito, L. Cocchi, J. Pujol, L.F. Fontenelle, D. Velakoulis, C. Pantelis, M. Yücel

ApoE and cholesterol in schizophrenia and bipolar disorder: comparison of grey and white matter and relation with APOE genotype
F. Vila-Rodriguez, W.G. Honer, S.M. Innis, C.L. Wellington, C.L. Beasley


Default mode alterations in posttraumatic stress disorder related to early-life trauma: a developmental perspective
J.K. Daniels, P. Frewen, M.C. McKinnon, R.A. Lanius


Thank you to those who reviewed submissions to the journal in 2010

Psychopharmacology for the Clinician

Myoclonus as an indicator of infection in patients with schizophrenia treated with clozapine
C.-S. Liang, T.-H. Hsieh

March 2011

J Psychiatry Neurosci 2011;36(2)


Biologic effects of mindfulness meditation: growing insights into neurobiologic aspects of the prevention of depression
S.N. Young

Review Papers

N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action
O. Dean, F. Giorlando, M. Berk

Pharmacogenetics of antidepressant response
S. Porcelli, A. Drago, C. Fabbri, S. Gibiino, R. Calati, A. Serretti

Research Papers

Elevation of cerebrospinal fluid interleukin-1ß in bipolar disorder
J. Söderlund, S.K. Olsson, M. Samuelsson, L. Walther-Jallow, C. Johansson, S. Erhardt, M. Landén, G. Engberg

Complementary diffusion tensor imaging study of the corpus callosum in patients with first-episode and chronic schizophrenia
X. Kong, X. Ouyang, H. Tao, H. Liu, L. Li, J. Zhao, Z. Xue, F. Wang, S. Jiang, B. Shan, Z. Liu

Reduced prepulse inhibition in adolescents at risk for psychosis: a 2-year follow-up study
T. Ziermans, P. Schothorst, M. Magnée, H. van Engeland, C. Kemner

Psychopharmacology for the Clinician

Identification and management of cryptic bipolarity in patients with TRD
V. Sharma

CCNP News and Views

In memoriam: Alan Boulton, 1936–2010
G.B. Baker, A. Holt, D.D. Mousseau