Table 2

Scanning methods and decreased fractional anisotropy regions of the studies included in this meta-analysis of diffusion tensor imaging studies of patients with MDD

	Methods

Study	Field, T	Acquisition voxel, mm³	No. of directions	No. of coordinates	Type of analysis	Coordinate system	Area of significantly decreased fractional anisotropy
Versace et al. (20)	3	Not stated	6	1	TBSS	MNI	Left inferior longitudinal fasciculi
Blood et al. (25)	3	1 × 1 × 1	6	12	VBA	MNI	Right anterior cingulate cortex Dorsolateral prefrontal cortex
Liu et al. (26)	1.5	Not stated	12	13	VBA	MNI	Middle temporal gyrus Middle frontal gyrus Fusiform gyrus et al.
Ma et al. (14)	1.5	1.9 × 1.9 × 4	13	4	VBA	Talairach	Right middle frontal gyrus Left lateral occipitotemporal gyrus Right parietal lobe Right angular gyri of parietal lobe
Abe et al. (27)	1.5	Not stated	6	2	VBA	MNI	Right anterior cingulate cortex Left frontal white matter
Steele et al. (28)	1.5	1.9 × 1.9 × 4	6	2	VBA	MNI	Right lateral temporal cortex Left uncinate fasciulus
Wu et al. (29)	1.5	2 × 2 × 2	13	3	VBA	MNI	Right superior longitudinal fasciculus Right middle frontal white matter Left inferior parietal lobe
Zou et al. (30)	3	1.9 × 1.9 × 3	15	2	VBA	Talairach	Left internal capsule Left superior longitudinal fasciculus
Ouyang et al. (31)	1.5	2 × 2 × 2	13	6	VBA	MNI	Bilateral medial frontal gyri Right subgyral frontal Temporal lobes Left middle frontal and cingulate gyri
Zhu et al. (21)	1.5	1 × 1 × 1	13	3	TBSS	MNI	Left anterior limb of internal capsule Right parahippocampal gyrus Left posterior cingulate cortex
Kieseppä et al. (22)	1.5	Not stated	12	2	TBSS	MNI	Left sagittal stratum Right anterior cingulum Right corpus callosum

MDD = major depressive disorder; MNI = Montreal Neurological Institute; TBSS = tract-based spatial statistics; VBA = voxel-based analysis.