The Original Social Network: White Matter and Social Cognition

Trends Cogn Sci. 2018 Jun;22(6):504-516. doi: 10.1016/j.tics.2018.03.005. Epub 2018 Apr 5.

Abstract

Social neuroscience has traditionally focused on the functionality of gray matter regions, ignoring the critical role played by axonal fiber pathways in supporting complex social processes. In this paper, we argue that research on white matter is essential for understanding a range of topics in social neuroscience, such as face processing, theory of mind, empathy, and imitation, as well as clinical disorders defined by aberrant social behavior, such as prosopagnosia, autism, and schizophrenia. We provide practical advice on how best to carry out these studies, which ultimately will substantially deepen our understanding of the neurobiological basis of social behavior.

Keywords: diffusion-weighted imaging; social cognition; social disorder; social neuroscience; structural connectivity; white matter.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Brain / anatomy & histology
  • Brain / diagnostic imaging*
  • Cognition*
  • Humans
  • Neural Pathways / anatomy & histology
  • Neural Pathways / diagnostic imaging
  • Social Behavior*
  • White Matter / anatomy & histology
  • White Matter / diagnostic imaging*