Odor identification in Huntington's disease patients and asymptomatic gene carriers

J Neuropsychiatry Clin Neurosci. 1997 Fall;9(4):598-600. doi: 10.1176/jnp.9.4.598.

Abstract

Odor identification was assessed in 20 Huntington's disease (HD) patients, 20 normal adults with the genetic mutation that causes HD, and 20 mutation-negative adults. The University of Pennsylvania Smell Identification Test (UPSIT) revealed substantial odor identification deficits only in HD patients.

Publication types

  • Clinical Trial
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Gene Expression
  • Heterozygote*
  • Humans
  • Huntington Disease / genetics*
  • Huntington Disease / psychology*
  • Male
  • Middle Aged
  • Mutation
  • Psychiatric Status Rating Scales
  • Smell / physiology*