User profiles for Alasdair M. Barr

Alasdair Barr

University of British Columbia
Verified email at interchange.ubc.ca
Cited by 10831

The need for speed: an update on methamphetamine addiction

AM Barr, WJ Panenka, GW MacEwan… - Journal of psychiatry and …, 2006 - jpn.ca
The psychostimulant methamphetamine (MA) is a highly addictive drug that has surged in
popularity over the last decade in North America. A burgeoning number of clandestine drug …

Methamphetamine use: a comprehensive review of molecular, preclinical and clinical findings

…, GW MacEwan, SW Flynn, WG Honer, AM Barr - Drug and alcohol …, 2013 - Elsevier
Methamphetamine (MA) is a highly addictive psychostimulant drug that principally affects
the monoamine neurotransmitter systems of the brain and results in feelings of alertness, …

Much of late life cognitive decline is not due to common neurodegenerative pathologies

PA Boyle, RS Wilson, L Yu, AM Barr… - Annals of …, 2013 - Wiley Online Library
Objective The pathologic indices of Alzheimer disease, cerebrovascular disease, and Lewy
body disease accumulate in the brains of older persons with and without dementia, but the …

Estradiol alleviates depressive-like symptoms in a novel animal model of post-partum depression

LAM Galea, JK Wide, AM Barr - Behavioural brain research, 2001 - Elsevier
… reduce immobility time compared to OVX controls (Barr and Galea, unpublished results). …
degree than that observed in the present study (Barr and Galea, unpublished results). To our …

Cognitive deficits in individuals with methamphetamine use disorder: A meta-analysis

S Potvin, J Pelletier, S Grot, C Hebert, AM Barr… - Addictive …, 2018 - Elsevier
Background Methamphetamine has long been considered as a neurotoxic substance causing
cognitive deficits. Recently, however, the magnitude and the clinical significance of the …

Stimulation of the ventral subiculum of the hippocampus evokes glutamate receptor‐mediated changes in dopamine efflux in the rat nucleus accumbens

…, CR Yang, SB Floresco, AM Barr… - European Journal of …, 1997 - Wiley Online Library
The effects of electrical stimulation of the ventral subiculum/CA1 region of the hippocampus
on changes in dopamine oxidation current (corresponding to dopamine efflux) in the nucleus …

Neuroleptic malignant syndrome: a review from a clinically oriented perspective

L Tse, AM Barr, V Scarapicchia… - Current …, 2015 - ingentaconnect.com
Neuroleptic malignant syndrome (NMS) is a rare but potentially life-threatening sideeffect that
can occur in response to treatment with antipsychotic drugs. Symptoms commonly include …

Cardiovascular side-effects of antipsychotic drugs: the role of the autonomic nervous system

JYT Leung, AM Barr, RM Procyshyn, WG Honer… - Pharmacology & …, 2012 - Elsevier
Cardiovascular disease is the leading cause of death in people with severe mental disorders,
and rates are proportionally greater than for other diseases such as cancer. Reports of …

A 'crash'course on psychostimulant withdrawal as a model of depression

AM Barr, A Markou, AG Phillips - Trends in pharmacological sciences, 2002 - cell.com
Most drugs of abuse generate diverse behavioral and neurochemical effects in mammals.
However, one feature common to many such drugs is the phenomenon of the withdrawal …

Withdrawal following repeated exposure to d-amphetamine decreases responding for a sucrose solution as measured by a progressive ratio schedule of …

AM Barr, AG Phillips - Psychopharmacology, 1999 - Springer
Numerous studies have shown that withdrawal from sustained high doses of psychostimulant
drugs such as cocaine or d-amphetamine produces depressive-like symptoms in both rats …