User profiles for Lena Palaniyappan
Lena K. PalaniyappanProfessor of Psychiatry, McGill University Verified email at mcgill.ca Cited by 9335 |
Does the salience network play a cardinal role in psychosis? An emerging hypothesis of insular dysfunction
L Palaniyappan, PF Liddle - Journal of Psychiatry and Neuroscience, 2012 - jpn.ca
The insular cortex is one of the brain regions that show consistent abnormalities in both
structural and functional neuroimaging studies of schizophrenia. In healthy individuals, the …
structural and functional neuroimaging studies of schizophrenia. In healthy individuals, the …
Brain-wide analysis of functional connectivity in first-episode and chronic stages of schizophrenia
…, ET Rolls, W Yang, L Palaniyappan… - Schizophrenia …, 2017 - academic.oup.com
Published reports of functional abnormalities in schizophrenia remain divergent due to lack
of staging point-of-view and whole-brain analysis. To identify key functional-connectivity …
of staging point-of-view and whole-brain analysis. To identify key functional-connectivity …
[PDF][PDF] Neural primacy of the salience processing system in schizophrenia
For effective information processing, two large-scale distributed neural networks appear to
be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex (…
be critical: a multimodal executive system anchored on the dorsolateral prefrontal cortex (…
Localized connectivity in depression: a meta-analysis of resting state functional imaging studies
Resting-state fMRI studies investigating the pathophysiology of depression have identified
prominent abnormalities in large-scale brain networks. However, it is unclear if localized …
prominent abnormalities in large-scale brain networks. However, it is unclear if localized …
Structural correlates of auditory hallucinations in schizophrenia: a meta-analysis
BACKGROUND: Despite being one of the most common symptoms of schizophrenia,
determining the neural correlates of auditory hallucinations still remains elusive with various …
determining the neural correlates of auditory hallucinations still remains elusive with various …
Resolving heterogeneity in schizophrenia through a novel systems approach to brain structure: individualized structural covariance network analysis
Reliable mapping of system-level individual differences is a critical first step toward precision
medicine for complex disorders such as schizophrenia. Disrupted structural covariance …
medicine for complex disorders such as schizophrenia. Disrupted structural covariance …
[HTML][HTML] Voxel-based, brain-wide association study of aberrant functional connectivity in schizophrenia implicates thalamocortical circuitry
Background: Wernicke’s concept of ‘sejunction’or aberrant associations among specialized
brain regions is one of the earliest hypotheses attempting to explain the myriad of symptoms …
brain regions is one of the earliest hypotheses attempting to explain the myriad of symptoms …
Brain surface anatomy in adults with autism: the relationship between surface area, cortical thickness, and autistic symptoms
Context Neuroimaging studies of brain anatomy in autism spectrum disorder (ASD) have
mostly been based on measures of cortical volume (CV). However, CV is a product of 2 distinct …
mostly been based on measures of cortical volume (CV). However, CV is a product of 2 distinct …
Repetitive transcranial magnetic stimulation versus electroconvulsive therapy for major depression: a systematic review and meta-analysis
J Ren, H Li, L Palaniyappan, H Liu, J Wang, C Li… - Progress in Neuro …, 2014 - Elsevier
Electroconvulsive therapy (ECT) is the most effective treatment of depression. During the last
decades repetitive transcranial magnetic stimulation (rTMS), an alternative method using …
decades repetitive transcranial magnetic stimulation (rTMS), an alternative method using …
Association of age, antipsychotic medication, and symptom severity in schizophrenia with proton magnetic resonance spectroscopy brain glutamate level: a mega …
…, I Nenadic, D Öngür, M Ota, L Palaniyappan… - JAMA …, 2021 - jamanetwork.com
Importance Proton magnetic resonance spectroscopy (1H-MRS) studies indicate that altered
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …
brain glutamatergic function may be associated with the pathophysiology of schizophrenia …