Advances in understanding the etiology of Parkinson disease have been driven by the
identification of causative mutations in families. Genetic analysis of an Australian family with three …

Aggression is commonly reported in individuals with Huntington's disease (HD). While
correlating factors for aggression are often speculated about, features that are associated with, …

We assessed the inter‐rater reliability of the 100‐point International Cooperative Ataxia Rating
Scale (ICARS). Three neurologists independently rated videotaped ICARS examinations …

Friedreich ataxia (FRDA), the commonest of the inherited ataxias, is a multisystem
neurodegenerative condition that affects ocular motor function. We assessed eye movement …

Friedreich ataxia (FRDA) is due to a triplet repeat expansion in FXN, resulting in deficiency
of the mitochondrial protein frataxin. Resveratrol is a naturally occurring polyphenol, …

Objective To quantify 18-month changes in white matter microstructure in premanifest (pre-HD)
and symptomatic Huntington's disease (symp-HD). To investigate baseline clinical, …

In transgenic mouse models of Huntington disease (HD) environmental enrichment significantly
delays disease onset. A questionnaire‐based survey of 154 adults with diagnosed HD (…

Speech disturbances (eg, altered prosody) have been described in symptomatic Huntington's
Disease (HD) individuals, however, the extent to which speech changes in gene positive …

Objective To investigate structural connectivity and the relationship between axonal microstructure
and clinical, cognitive, and motor functions in premanifest (pre-HD) and symptomatic (…

Objectives To measure iron accumulation in the basal ganglia in Huntington's disease (HD)
using quantitative susceptibility mapping (QSM), and to ascertain its relevance in terms of …