Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa

…, V Ricca, S Ripatti, F Ritschel… - Nature …, 2019 - nature.com
Characterized primarily by a low body-mass index, anorexia nervosa is a complex and
serious illness 1 , affecting 0.9–4% of women and 0.3% of men 2 , 3 – 4 , with twin-based …

Global cortical thinning in acute anorexia nervosa normalizes following long-term weight restoration

JA King, D Geisler, F Ritschel, I Boehm, M Seidel… - Biological …, 2015 - Elsevier
Background Anorexia nervosa (AN) is a serious eating disorder characterized by self-starvation,
extreme weight loss, and alterations in brain structure. Structural magnetic resonance …

Elevated cognitive control over reward processing in recovered female patients with anorexia nervosa

S Ehrlich, D Geisler, F Ritschel, JA King, M Seidel… - Journal of Psychiatry and …, 2015 - jpn.ca
Background: Individuals with anorexia nervosa are thought to exert excessive self-control to
inhibit primary drives. Methods: This study used functional MRI (fMRI) to interrogate …

[HTML][HTML] Increased resting state functional connectivity in the fronto-parietal and default mode network in anorexia nervosa

I Boehm, D Geisler, JA King, F Ritschel… - Frontiers in behavioral …, 2014 - frontiersin.org
The etiology of anorexia nervosa (AN) is poorly understood. Results from functional brain
imaging studies investigating the neural profile of AN using cognitive and emotional task …

A naturalistic examination of negative affect and disorder-related rumination in anorexia nervosa

M Seidel, J Petermann, S Diestel, F Ritschel… - European Child & …, 2016 - Springer
In anorexia nervosa (AN), volitional inhibition of rewarding behaviors, such as eating, involves
a conflict between the desire to suppress appetite and the inherent motive to consume. …

[HTML][HTML] The real-life costs of emotion regulation in anorexia nervosa: a combined ecological momentary assessment and fMRI study

M Seidel, JA King, F Ritschel, I Boehm… - Translational …, 2018 - nature.com
Regulation of emotions is necessary for successful attainment of short-term and long-term
goals. However, over-regulation may also have its costs. In anorexia nervosa (AN), forgoing …

Shared genetic risk between eating disorder‐and substance‐use‐related phenotypes: Evidence from genome‐wide association studies

…, V Ricca, S Ripatti, F Ritschel… - Addiction …, 2021 - Wiley Online Library
Eating disorders and substance use disorders frequently co‐occur. Twin studies reveal
shared genetic variance between liabilities to eating disorders and substance use, with the …

Reduced functional connectivity in the thalamo‐insular subnetwork in patients with acute anorexia nervosa

…, V Borchardt, I Boehm, M Seidel, F Ritschel… - Human Brain …, 2015 - Wiley Online Library
The neural underpinnings of anorexia nervosa (AN) are poorly understood. Results from
existing functional brain imaging studies using disorder‐relevant food‐ or body‐stimuli have …

Altered neural efficiency of decision making during temporal reward discounting in anorexia nervosa

JA King, D Geisler, F Bernardoni, F Ritschel… - Journal of the American …, 2016 - Elsevier
Objective The ability of individuals with anorexia nervosa (AN) to resist hunger and restrict
caloric intake is often believed to reflect an unusual amount of self-control. However, the …

Altered medial frontal feedback learning signals in anorexia nervosa

…, D Geisler, JA King, AH Javadi, F Ritschel… - Biological …, 2018 - Elsevier
Background In their relentless pursuit of thinness, individuals with anorexia nervosa (AN)
engage in maladaptive behaviors (restrictive food choices and overexercising) that may …