Importance Short-term and long-term persistent postacute sequelae of COVID-19 (PASC)
have not been systematically evaluated. The incidence and evolution of PASC are dependent …

Maintaining alertness is critical for safe and successful performance of most human activities.
Consequently, microsleeps during continuous visuomotor tasks, such as driving, can be …

Trans‐neuronal propagation of mutant huntingtin protein contributes to the organised
spread of cortico‐striatal degeneration and disconnection in Huntington's disease (HD). We …

Light improves mood. The amygdala plays a critical role in regulating emotion, including fear-related
responses. In rodents the amygdala receives direct light input from the retina, and …

Circadian disruption is associated with poor health outcomes, including sleep and mood
disorders. The suprachiasmatic nucleus (SCN) of the anterior hypothalamus acts as the master …

Objective To quantify 18-month changes in white matter microstructure in premanifest (pre-HD)
and symptomatic Huntington's disease (symp-HD). To investigate baseline clinical, …

Objective To investigate structural connectivity and the relationship between axonal microstructure
and clinical, cognitive, and motor functions in premanifest (pre-HD) and symptomatic (…

Background: Functional neural impairments have been documented in people with symptomatic
Huntington disease (symp-HD) and in premanifest gene carriers (pre-HD). This study …

IMAGE-HD is an Australian based multi-modal longitudinal magnetic resonance imaging (MRI)
study in premanifest and early symptomatic Huntington’s disease (pre-HD and symp-HD, …

We characterized 30-month longitudinal change in functional activation and connectivity
during working memory in premanifest (pre-HD) and symptomatic (symp-HD) Huntington’s …