Background Severe mental illness (SMI), including schizophrenia, bipolar disorder and severe
depression, is responsible for a substantial proportion of disability in the population. This …

Importance Findings of cognitive impairment in major depressive disorder (MDD), including
remitted MDD, raise the question whether impaired cognition is part of preexisting …

Major shifts taking place in the world economy are having an effect on rural communities.
There are indications that local and regional areas will become increasingly important in the …

Background Attention‐deficit/hyperactivity disorder (ADHD) and lower cognitive ability have
been linked with increased likelihood of exposure to adversity. We hypothesized that these …

BackgroundPsychotic symptoms are common in children and adolescents and may be early
manifestations of liability to severe mental illness (SMI), including schizophrenia. SMI and …

BACKGROUND: Stimulants, such as methylphenidate, are among the most commonly used
medications in children and adolescents. Psychotic symptoms have been reported as rare …

Capsaicin solution was applied for 15 min around a 1 cm length of sciatic nerve in the mid
upper leg of adult rats.

Aim Approximately 50% of individuals with first‐episode psychosis meet criteria for a
substance use disorder and these concurrent disorders are associated with worse long‐term …

Affective lability, defined as the propensity to experience excessive and unpredictable changes
in mood, has been proposed as a potential transdiagnostic predictor of major mood and …

Background It has been suggested that offspring of parents with bipolar disorder are at
increased risk for disruptive mood dysregulation disorder (DMDD), but the specificity of this …