BACKGROUND: Neuroimaging studies have shown that major depressive disorder (MDD)
is accompanied by structural and functional abnormalities in specific brain regions and …

Background: Many studies using diffusion tensor imaging (DTI) have demonstrated impaired
white matter integrity in patients with major depressive disorder (MDD), with significant …

Context Most of what we know about antipsychotic drug effects is at the receptor level, distal
from the neural system effects that mediate their clinical efficacy. Studying cerebral function …

Objective: The authors used resting-state functional connectivity MRI to evaluate brain
networks in patients with refractory and nonrefractory major depressive disorder. Method: In a …

Despite significant advances in the treatment of major depression, there is a high degree of
variability in how patients respond to treatment. Approximately 70% of patients show some …

Purpose.: Weexamined changes of the central nervous system in patients with advanced
primary open-angle glaucoma (POAG). Methods.: The clinical observational study included 15 …

Objective: Suicide is a major social and public health problem, but its neurobiology in major
depressive disorder is poorly understood. The purpose of this study was to use magnetic …

Background: Obsessive–compulsive disorder (OCD) is a common neuropsychiatric disorder
that is characterized by recurrent intrusive thoughts, ideas or images and repetitive ritualistic …

Background: The neurobiology of suicide is largely unknown. Studies of white matter tracts in
patients with a history of suicidal behaviour have shown alteration in the left anterior limb of …

Leukemia inhibitory factor (LIF) receptor signaling limits the severity of inflammatory demyelination
in experimental autoimmune encephalomyelitis, a T-cell dependent animal model of …