Assessment of executive functions: Review of instruments and identification of critical issues
RCK Chan, D Shum, T Toulopoulou… - Archives of clinical …, 2008 - academic.oup.com
“Executive functions” is an umbrella term for functions such as planning, working memory,
inhibition, mental flexibility, as well as the initiation and monitoring of action. The impairment of …
inhibition, mental flexibility, as well as the initiation and monitoring of action. The impairment of …
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
…, VJ Carr, D Castle, SV Catts, KD Chambert, RCK Chan… - Nature, 2022 - nature.com
Schizophrenia has a heritability of 60–80% 1 , much of which is attributable to common risk
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …
alleles. Here, in a two-stage genome-wide association study of up to 76,755 individuals with …
[PDF][PDF] Modeling linkage disequilibrium increases accuracy of polygenic risk scores
…, N Carrera, SV Catts, KD Chambert, RCK Chan… - The american journal of …, 2015 - cell.com
Polygenic risk scores have shown great promise in predicting complex disease risk and will
become more accurate as training sample sizes increase. The standard approach for …
become more accurate as training sample sizes increase. The standard approach for …
[HTML][HTML] Clozapine alone versus clozapine and risperidone with refractory schizophrenia
…, AE Thornton, EYH Chen, RCK Chan… - … England Journal of …, 2006 - Mass Medical Soc
Background The treatment of schizophrenia with multiple antipsychotic drugs is common,
but the benefits and risks are not known. Methods In a randomized, double-blind study, we …
but the benefits and risks are not known. Methods In a randomized, double-blind study, we …
Neurological soft signs in schizophrenia: a meta-analysis
Background: Neurological soft signs (NSS) are hypothesized as candidate endophenotypes
for schizophrenia, but their prevalence and relations with clinical and demographic data are …
for schizophrenia, but their prevalence and relations with clinical and demographic data are …
[PDF][PDF] Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases
…, N Carrera, SV Catts, KD Chambert, RCK Chan… - The American Journal of …, 2014 - cell.com
Regulatory and coding variants are known to be enriched with associations identified by
genome-wide association studies (GWASs) of complex disease, but their contributions to trait …
genome-wide association studies (GWASs) of complex disease, but their contributions to trait …
Cross-cultural validation of the depression anxiety stress scale–21 in China.
…, DL Neumann, DHK Shum, RCK Chan - Psychological …, 2016 - psycnet.apa.org
The gap between the demand and delivery of mental health services in mainland China can
be reduced by validating freely available and psychometrically sound psychological …
be reduced by validating freely available and psychometrically sound psychological …
Is depression a disconnection syndrome? Meta-analysis of diffusion tensor imaging studies in patients with MDD
…, W Kuang, M Du, S Lui, Q Yue, RCK Chan… - Journal of Psychiatry and …, 2013 - jpn.ca
Background: Many studies using diffusion tensor imaging (DTI) have demonstrated impaired
white matter integrity in patients with major depressive disorder (MDD), with significant …
white matter integrity in patients with major depressive disorder (MDD), with significant …
A meta-analysis of working memory impairments in autism spectrum disorders
…, DHK Shum, T van Amelsvoort, RCK Chan - Neuropsychology …, 2017 - Springer
Autism spectrum disorders (ASD) are characterized by executive dysfunction, and working
memory (WM) comprises one core component of executive function. Many studies have …
memory (WM) comprises one core component of executive function. Many studies have …
Neuropsychological measures of executive function and antisocial behavior: A meta‐analysis
JM Ogilvie, AL Stewart, RCK Chan, DHK Shum - Criminology, 2011 - Wiley Online Library
A meta‐analysis was performed to quantify the association between antisocial behavior (ASB)
and performance on neuropsychological executive functioning (EF) measures. This meta‐…
and performance on neuropsychological executive functioning (EF) measures. This meta‐…