User profiles for Rudolf Uher

Rudolf Uher

Dalhousie University
Verified email at dal.ca
Cited by 37454

Genetic sensitivity to the environment: the case of the serotonin transporter gene and its implications for studying complex diseases and traits

A Caspi, AR Hariri, A Holmes, R Uher… - American journal of …, 2010 - Am Psychiatric Assoc
Evidence of marked variability in response among people exposed to the same environmental
risk implies that individual differences in genetic susceptibility might be at work. The study …

Time for united action on depression: a Lancet–World Psychiatric Association Commission

…, BWJH Penninx, S Xiao, M Trivedi, R Uher… - The Lancet, 2022 - thelancet.com
“Depression is a disorder of mood, so mysteriously painful and elusive in the way it becomes
known to the self—to the mediating intellect—as to verge close to being beyond description…

Canadian Network for Mood and Anxiety Treatments (CANMAT) 2016 clinical guidelines for the management of adults with major depressive disorder: section 3 …

…, NL Pearson, AV Ravindran, R Uher… - The Canadian …, 2016 - journals.sagepub.com
Background: The Canadian Network for Mood and Anxiety Treatments (CANMAT) conducted
a revision of the 2009 guidelines by updating the evidence and recommendations. The …

Childhood maltreatment predicts unfavorable course of illness and treatment outcome in depression: a meta-analysis

V Nanni, R Uher, A Danese - American Journal of Psychiatry, 2012 - Am Psychiatric Assoc
Objectives: Evidence suggests that childhood maltreatment may negatively affect not only
the lifetime risk of depression but also clinically relevant measures of depression, such as …

Risk of mental illness in offspring of parents with schizophrenia, bipolar disorder, and major depressive disorder: a meta-analysis of family high-risk studies

D Rasic, T Hajek, M Alda, R Uher - Schizophrenia bulletin, 2014 - academic.oup.com
Objective: Offspring of parents with severe mental illness (SMI; schizophrenia, bipolar
disorder, major depressive disorder) are at an increased risk of developing mental illness. We …

Evidence-based guidelines for treating depressive disorders with antidepressants: a revision of the 2008 British Association for Psychopharmacology guidelines

…, J Scott, D Taylor, R Uher… - Journal of …, 2015 - journals.sagepub.com
A revision of the 2008 British Association for Psychopharmacology evidence-based
guidelines for treating depressive disorders with antidepressants was undertaken in order to …

The moderation by the serotonin transporter gene of environmental adversity in the aetiology of mental illness: review and methodological analysis

R Uher, P McGuffin - Molecular psychiatry, 2008 - nature.com
Gene–environmental interaction (G× E) between a common functional polymorphism in the
promoter region of the serotonin transporter gene (5-HTT) and environmental adversity on …

Medial prefrontal cortex activity associated with symptom provocation in eating disorders

R Uher, T Murphy, MJ Brammer… - American Journal of …, 2004 - Am Psychiatric Assoc
OBJECTIVE: The authors sought to identify neural correlates of eating disorders in order to
contribute to the debate on the genesis and classification of eating disorders and provide …

The contribution of prenatal and postnatal maternal anxiety and depression to child maladjustment

ED Barker, SR Jaffee, R Uher… - Depression and …, 2011 - Wiley Online Library
Background: The adverse effect of both pre‐ and post‐natal maternal anxiety and depression
on the development of offspring is shown by a large body of research. No published studies…

[HTML][HTML] Candidate genes expression profile associated with antidepressants response in the GENDEP study: differentiating between baseline 'predictors' and …

A Cattaneo, M Gennarelli, R Uher, G Breen… - …, 2013 - nature.com
To improve the ‘personalized-medicine’approach to the treatment of depression, we need to
identify biomarkers that, assessed before starting treatment, predict future response to …