Faithful transmission of genetic material in eukaryotic cells requires not only accurate DNA
replication and chromosome distribution but also the ability to sense and repair spontaneous …

Altered resting-state functional connectivity (rsFC) has been noted in large-scale functional
networks in attention-deficit/hyperactivity disorder (ADHD). However, identifying consistent …

Cancer drugs are broadly classified into two categories: cytotoxic chemotherapies and targeted
therapies that specifically modulate the activity of one or more proteins involved in cancer…

Photodynamic therapy (PDT) has been applied in cancer treatment by utilizing reactive
oxygen species to kill cancer cells. However, a high concentration of glutathione (GSH) is …

The maintenance of genome integrity is essential for the proper function and survival of all
organisms. Human cells have evolved prompt and efficient DNA damage response to …

Photothermal therapy (PTT) has been extensively developed as an effective approach
against cancer. However, PTT can trigger inflammatory responses, in turn simulating tumor …

Mitophagy is a process in which cells remove dysfunctional mitochondria and recycle their
constituents in a lysosome-dependent manner. To probe this process, two different …

Chemotherapy for patients with metastatic colorectal cancer (CRC) is the standard of care, but
ultimately nearly all patients develop drug resistance. Understanding the mechanisms that …

Stimuli-responsive biomaterials that contain logic gates hold great potential for detecting and
responding to pathological markers as part of clinical therapies. However, a major barrier is …

Aptamers are powerful candidates for molecular imaging and targeted therapy of cancer
based on such appealing features as high binding affinity, high specificity, site-specific …