Prediction, psychosis, and the cerebellum

T Moberget, RB Ivry - Biological Psychiatry: Cognitive Neuroscience and …, 2019 - Elsevier
An increasingly influential hypothesis posits that many of the diverse symptoms of psychosis
can be viewed as reflecting dysfunctional predictive mechanisms. Indeed, to perceive …

[HTML][HTML] Cerebellar-motor dysfunction in schizophrenia and psychosis-risk: the importance of regional cerebellar analysis approaches

JA Bernard, VA Mittal - Frontiers in psychiatry, 2014 - frontiersin.org
Motor abnormalities in individuals with schizophrenia and those at-risk for psychosis are
well documented. An accumulating body of work has also highlighted motor abnormalities …

Cerebellar volume and cerebellocerebral structural covariance in schizophrenia: a multisite mega-analysis of 983 patients and 1349 healthy controls

T Moberget, NT Doan, D Alnæs, T Kaufmann… - Molecular …, 2018 - nature.com
Although cerebellar involvement across a wide range of cognitive and neuropsychiatric
phenotypes is increasingly being recognized, previous large-scale studies in schizophrenia …

Cerebellar gray matter volume is associated with cognitive function and psychopathology in adolescence

T Moberget, D Alnæs, T Kaufmann, NT Doan… - Biological …, 2019 - Elsevier
Background Accumulating evidence supports cerebellar involvement in mental disorders,
such as schizophrenia, bipolar disorder, depression, anxiety disorders, and attention …

[PDF][PDF] A role for the cerebellum in motor-triggered alleviation of anxiety

XY Zhang, WX Wu, LP Shen, MJ Ji, PF Zhao, L Yu… - Neuron, 2024 - cell.com
Physical exercise is known to reduce anxiety, but the underlying brain mechanisms remain
unclear. Here, we explore a hypothalamo-cerebello-amygdalar circuit that may mediate …

Oculomotor prediction: a window into the psychotic mind

KN Thakkar, VA Diwadkar, M Rolfs - Trends in Cognitive Sciences, 2017 - cell.com
Psychosis–an impaired contact with reality–is a hallmark of schizophrenia. Many psychotic
symptoms are associated with disruptions in agency–the sense that 'I'cause my actions. A …

Visuomotor learning from postdictive motor error

J Masselink, M Lappe - Elife, 2021 - elifesciences.org
Sensorimotor learning adapts motor output to maintain movement accuracy. For saccadic
eye movements, learning also alters space perception, suggesting a dissociation between …

Disrupted corollary discharge in schizophrenia: Evidence from the oculomotor system

KN Thakkar, M Rolfs - Biological Psychiatry: Cognitive Neuroscience and …, 2019 - Elsevier
Corollary discharge (CD) signals are motor-related signals that exert an influence on
sensory processing. They allow mobile organisms to predict the sensory consequences of …

[HTML][HTML] Facilitation of sensorimotor temporal recalibration mechanisms by cerebellar tDCS in patients with schizophrenia spectrum disorders and healthy individuals

CV Schmitter, B Straube - Scientific Reports, 2024 - nature.com
Core symptoms in patients with schizophrenia spectrum disorders (SSD), like hallucinations
or ego-disturbances, have been associated with a failure of internal forward models to …

Abnormalities in motor adaptation to different types of perturbations in schizophreniaperturbations in schizophrenia

H Diao, J Ma, Y Jia, H Jia, K Wei - Schizophrenia Research, 2024 - Elsevier
Schizophrenia is a mental health disorder that often includes psychomotor disturbances,
impacting how individuals adjust their motor output based on the cause of motor errors …