Background: Functional neural impairments have been documented in people with
symptomatic Huntington disease (symp-HD) and in premanifest gene carriers (pre-HD). This …

Background. Functional magnetic resonance imaging (fMRI) of multiple neural networks
during the brain's 'resting state'could facilitate biomarker development in patients with …

Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative
disorder characterized by motor, cognitive, and psychiatric symptoms. Using resting‐state …

Background This study aimed to characterize, for the first time, 18 month longitudinal
changes in both functional activation and functional connectivity during working memory in …

Abstract Background Huntington's Disease (HD) is characterized by motor, cognitive and
psychiatric dysfunction. Functional MRI (fMRI) provides new insight into the pathologic …

Resting‐state functional magnetic resonance imaging (rs‐fMRI) has the potential to shed
light on the pathophysiological mechanisms of Huntington's disease (HD), paving the way to …

Dynamic functional network connectivity (dFNC) is an expansion of traditional, static FNC
that measures connectivity variation among brain networks throughout scan duration. We …

In clinically presymptomatic individuals with the Huntington's disease (HD) gene mutation,
functional neuroimaging data have suggested a dysfunction of multiple cortical and …

Previous MRI studies of functional connectivity in pre-symptomatic mutation carriers of
Huntington's disease (HD) have shown dysfunction of the Default-Mode Network (DMN). No …

The default-mode network (DMN) refers to as a set of brain regions which are active when
the brain does not engage in a cognitive task and which are deactivated with task-related …