Psychotic symptoms are associated with lower cortical folding in youth at risk for mental illness
V Drobinin, H Van Gestel, A Zwicker… - Journal of Psychiatry and …, 2020 - jpn.ca
Background: Cortical folding is essential for healthy brain development. Previous studies
have found regional reductions in cortical folding in adult patients with psychotic illness. It is …
have found regional reductions in cortical folding in adult patients with psychotic illness. It is …
Psychotic like experiences in healthy adolescents are underpinned by lower fronto-temporal cortical gyrification: a study from the IMAGEN consortium
Abstract Background and Hypothesis Psychotic Like Experiences (PLEs) are widely
prevalent in children and adolescents and increase the risk of developing psychosis …
prevalent in children and adolescents and increase the risk of developing psychosis …
Disorganized gyrification network properties during the transition to psychosis
T Das, S Borgwardt, DJ Hauke, F Harrisberger… - JAMA …, 2018 - jamanetwork.com
Importance There is urgent need to improve the limited prognostic accuracy of clinical
instruments to predict psychosis onset in individuals at clinical high risk (CHR) for psychosis …
instruments to predict psychosis onset in individuals at clinical high risk (CHR) for psychosis …
Reduced brain cortical folding in schizophrenia revealed in two independent samples
The cerebral cortex is highly convoluted, and principal folding patterns are determined early
in life. Degree of cortical folding in adult life may index aberrations in brain development …
in life. Degree of cortical folding in adult life may index aberrations in brain development …
Increased parietal and occipital lobe gyrification predicts conversion to syndromal psychosis in a clinical high-risk cohort
Background Local gyrification index (lGI), indicative of the degree of cortical folding is a
proxy marker for early cortical neurodevelopmental abnormalities. We studied the difference …
proxy marker for early cortical neurodevelopmental abnormalities. We studied the difference …
Cortical gyrification, psychotic-like experiences, and cognitive performance in nonclinical subjects
U Evermann, C Gaser, B Besteher… - Schizophrenia …, 2020 - academic.oup.com
Background Psychotic-like experiences (PLE) are present in nonclinical populations, yet
their association with brain structural variation, especially markers of early …
their association with brain structural variation, especially markers of early …
Cortical morphometry in the psychosis risk period: a comprehensive perspective of surface features
Background Gyrification features reflect brain development in the early prenatal
environment. Clarifying the nature of these features in psychosis can help shed light on the …
environment. Clarifying the nature of these features in psychosis can help shed light on the …
Increased occipital gyrification and development of psychotic disorders in individuals with an at-risk mental state: a multicenter study
D Sasabayashi, Y Takayanagi, T Takahashi, S Koike… - Biological …, 2017 - Elsevier
Background Anomalies of brain gyrification have been reported in schizophrenia, possibly
reflecting its neurodevelopmental pathology. However, it remains elusive whether …
reflecting its neurodevelopmental pathology. However, it remains elusive whether …
Cortical folding defects as markers of poor treatment response in first-episode psychosis
L Palaniyappan, TR Marques, H Taylor… - JAMA …, 2013 - jamanetwork.com
Importance At present, no reliable predictors exist to distinguish future responders from
nonresponders to treatment during the first episode of psychosis. Among potential …
nonresponders to treatment during the first episode of psychosis. Among potential …
Abnormal cortical folding in high-risk individuals: a predictor of the development of schizophrenia?
JM Harris, H Whalley, S Yates, P Miller… - Biological …, 2004 - Elsevier
BACKGROUND: A number of studies have found localized differences in the appearance
and extent of cortical folding between the brains of schizophrenic patients and healthy …
and extent of cortical folding between the brains of schizophrenic patients and healthy …