The use of medroxyprogesterone acetate for the treatment of sexually inappropriate behaviour in patients with dementia

The use of medroxyprogesterone acetate for the treatment of sexually inappropriate behaviour in patients with dementia

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J Psychiatry Neurosci 2006;31(2):132-4

Stacy Anderson Light, MD; Suzanne Holroyd, MD

Department of Psychiatric Medicine, University of Virginia, Charlottesville, Va.

Abstract

Sexually inappropriate behaviour in a patient with dementia can be a problem for caregivers. Little research has been done concerning treatment for this behavioural disorder. The hormone medroxyprogesterone acetate (MPA) is a known, but infrequently used, treatment option. We describe a series of 5 cases in which MPA was used successfully to control inappropriate sexual behaviours in men with dementia.

Résumé

Un comportement sexuel inapproprié chez un patient atteint de démence peut poser un problème pour les soignants. Il s’est fait peu de recherches sur le traitement de ce trouble du comportement. L’acétate de médroxyprogestérone (MPA) constitue un traitement hormonal possible connu mais peu utilisé. Nous décrivons une série de cinq cas où l’on a utilisé le MPA avec succès pour contrôler un comportement sexuel inapproprié chez des hommes atteints de démence.


Medical subject headings: dementia; disinhibition; medroxyprogesterone acetate; sexual disorder.

Competing interests: None declared.

Submitted Dec. 30, 2004; Revised July 13, 2005; Accepted Aug. 16, 2005

Correspondence to: Dr. Stacy Anderson Light, c/o Dr. Suzanne Holroyd, Department of Psychiatric Medicine, University of Virginia, Box 800623, Charlottesville VA 22908; fax 434 924-5149;sh4s@virginia.edu