September 2010

J Psychiatry Neurosci 2010;35(5)


Will there be a role for neuroimaging in clinical psychiatry?
G.M. MacQueen

Research Papers

Oxidative damage to RNA but not DNA in the hippocampus of patients with major mental illness
Y. Che, J.-F. Wang, L. Shao, L.T. Young

Osteoprotegerin levels in patients with severe mental disorders
S. Hope, I. Melle, P. Aukrust, I. Agartz, S. Lorentzen, N.E. Steen, S. Djurovic, T. Ueland, O.A. Andreassen

Orbitofrontal volume reductions during emotion recognition in patients with major depression
J. Scheuerecker, E.M. Meisenzahl, N. Koutsouleris, M. Roesner, V. Schöpf, J. Linn, M. Wiesmann, H. Brückmann, H.- J. Möller, T. Frodl

Neural correlates of set-shifting: decomposing executive functions in schizophrenia
A. Wilmsmeier, P. Ohrmann, T. Suslow, A. Siegmund, K. Koelkebeck, M. Rothermundt, H. Kugel, V. Arolt, J. Bauer, A. Pedersen

Regional differences in cerebral perfusion associated with the α-2A-adrenergic receptor genotypes in attention deficit hyperactivity disorder
B.-N. Kim, J.-W. Kim, H. Kang, S.-C. Cho, M.-S. Shin, H.-J. Yoo, S.-B. Hong, D.S. Lee

Structural changes in the hippocampus in major depressive disorder: contributions of disease and treatment
N.V. Malykhin, R. Carter, P. Seres, N.J. Coupland

Psychopharmacology for the Clinician

Autism spectrum disorders, schizo phrenia and diagnostic confusion
M.R. Woodbury-Smith, K. Boyd, P. Szatmari

March 2009

J Psychiatry Neurosci 2009;34(2)


NeuroAIDS: a watershed for mental health and nervous system disorders
J.A. McCombe, F. Noorbakhsh, C. Buchholz, M. Trew, C. Power

Review paper

Candidate genes and neuropsychological phenotypes in children with ADHD: review of association studies
O. Kebir, K. Tabbane, S. Sengupta, R. Joober

Research Papers

2007 CCNP Young Investigator Award paper: Relation between emotional face memory and social anhedonia in schizophrenia
P.-O. Harvey, M. Bodnar, K. Sergerie, J. Armony, M. Lepage

Latent deleterious effects of binge drinking over a short period of time revealed only by electrophysiological measures
P. Maurage, M. Pesenti, P. Philippot, F. Joassin, S. Campanella

Acute effects of repetitive transcranial magnetic stimulation on attentional control are related to antidepressant outcomes
M.-A. Vanderhasselt, R. De Raedt, L. Leyman, C. Baeken

Cortical folding in patients with bipolar disorder or unipolar depression
J. Penttilä, M.-L. Paillère-Martinot, J.-L. Martinot, D. Ringuenet, M. Wessa, J. Houenou, T. Gallarda, F. Bellivier, A. Galinowski, P. Bruguière, F. Pinabel, M. Leboyer, J.-P. Olié, E. Duchesnay, E. Artiges, J.-F. Mangin, A. Cachia

Association of total tau and phosphorylated tau 181 protein levels in cerebrospinal fluid with cerebral atrophy in mild cognitive impairment and Alzheimer disease
P.A. Thomann, E. Kaiser, P. Schönknecht, J. Pantel, M. Essig, J. Schröder


Glutamate and dopamine components in schizophrenia
P. Seeman

Psychopharmacology for the Clinician

Do serum lipids predict response to clozapine treatment?
R.M. Procyshyn, W.G. Honer, A.M. Barr

January 2009

J Psychiatry Neurosci 2009;34(1)


Has the time come for clinical trials on the antidepressant effect of vitamin D?
S.N. Young

Review Paper

2008 CCNP Heinz Lehmann Award paper: Cascading effects of stressors and inflammatory immune system activation: implications for major depressive disorder
H. Anisman

Research Papers

Neural synchrony in patients with a first episode of schizophrenia: tracking relations with grey matter and symptom profile
L.M. Williams, T.J. Whitford, E. Gordon, L. Gomes, K.J. Brown, A.W.F. Harris

Genotype over diagnosis in amygdala responsiveness: affective processing in social anxiety disorder
T. Furmark, S. Henningsson, L. Appel, F. Åhs, C. Linnman, A. Pissiota, V. Faria, L. Oreland, M. Bani, E. Merlo Pich, E. Eriksson, M. Fredrikson

A meta-analysis examining clinical predictors of hippocampal volume in patients with major depressive disorder
M.C. McKinnon, K. Yucel, A. Nazarov, G.M. MacQueen


A new wave in the genetics of psychiatric disorders: the copy number variant tsunami
R. Joober, P. Boksa

Brief Report

High-frequency repetitive transcranial magnetic stimulation to the cerebellum and implicit processing of happy facial expressions
D.J.L.G. Schutter, D. Enter, S.S. Hoppenbrouwers

CCNP News and Views

The 31st Annual Meeting of the Canadian College of Neuropsychopharmacology
C. Flores, L. Zawertailo, J. Meyer, M. Leyton


2008 Reviewers

Psychopharmacology for the Clinician

Optimal use of antidepressants: When to act?
P. Blier

November 2010

J Psychiatry Neurosci 2010;35(6)


Epigenetics in mental illness: Hope or hype?
P.R. Albert

Research Papers

Perceived early-life maternal care and the cortisol response to repeated psychosocial stress
V. Engert, S.I. Efanov, K. Dedovic, A. Duchesne, A. Dagher, J.C. Pruessner

Impact of cognitive performance on the reproducibility of fMRI activation in schizophrenia
O. Maïza, B. Mazoyer, P.-Y. Hervé, A. Razafimandimby, S. Dollfus, N. Tzourio-Mazoyer

Neural responses to emotional and neutral facial expressions in chronically violent men
D.A. Pardini, M. Phillips

Dysregulation of the sympathetic nervous system, hypothalamic–pituitary–adrenal axis and executive function in individuals at risk for suicide
A. McGirr, G. Diaconu, M.T. Berlim, J.C. Pruessner, R. Sablé, S. Cabot, G. Turecki

Brief Report

White-matter abnormalities in adolescents with long-term inhalant and cannabis use: a diffusion magnetic resonance imaging study
M. Yücel, A. Zalesky, M.J. Takagi, E. Bora, A. Fornito, M. Ditchfield, G.F. Egan, C. Pantelis, D.I. Lubman

Psychopharmacology for the Clinician

Is there a role for estrogen in treating depression during menopause?
C.N. Soares, B.N. Frey

January 2011

J Psychiatry Neurosci 2011;36(1)


Possible directions for the discovery of new antidepressant treatments
S.N. Young

Research Papers

Effects of trauma-related cues on pain processing in posttraumatic stress disorder: an fMRI investigation
M.J.S. Mickleborough, J.K. Daniels, N.J. Coupland, R. Kao, P.C. Williamson, U.F. Lanius, K. Hegadoren, A. Schore, M. Densmore, T. Stevens, R.A. Lanius

Structural MRI correlates for vulnerability and resilience to major depressive disorder
F. Amico, E. Meisenzahl, N. Koutsouleris, M. Reiser, H.-J. Möller, T. Frodl

Abnormal small-world architecture of top–down control networks in obsessive–compulsive disorder
T. Zhang, J. Wang, Y. Yang, Q. Wu, B. Li, L. Chen, Q. Yue, H. Tang, C. Yan, S. Lui, X. Huang, R.C.K. Chan, Y. Zang, Y. He, Q. Gong

Pervasive microstructural abnormalities in autism: a DTI study
W.B. Groen, J.K. Buitelaar, R.J. van der Gaag, M.P. Zwiers

White matter microstructure in patients with obsessive–compulsive disorder
E. Bora, B.J. Harrison, A. Fornito, L. Cocchi, J. Pujol, L.F. Fontenelle, D. Velakoulis, C. Pantelis, M. Yücel

ApoE and cholesterol in schizophrenia and bipolar disorder: comparison of grey and white matter and relation with APOE genotype
F. Vila-Rodriguez, W.G. Honer, S.M. Innis, C.L. Wellington, C.L. Beasley


Default mode alterations in posttraumatic stress disorder related to early-life trauma: a developmental perspective
J.K. Daniels, P. Frewen, M.C. McKinnon, R.A. Lanius


Thank you to those who reviewed submissions to the journal in 2010

Psychopharmacology for the Clinician

Myoclonus as an indicator of infection in patients with schizophrenia treated with clozapine
C.-S. Liang, T.-H. Hsieh

March 2011

J Psychiatry Neurosci 2011;36(2)


Biologic effects of mindfulness meditation: growing insights into neurobiologic aspects of the prevention of depression
S.N. Young

Review Papers

N-acetylcysteine in psychiatry: current therapeutic evidence and potential mechanisms of action
O. Dean, F. Giorlando, M. Berk

Pharmacogenetics of antidepressant response
S. Porcelli, A. Drago, C. Fabbri, S. Gibiino, R. Calati, A. Serretti

Research Papers

Elevation of cerebrospinal fluid interleukin-1ß in bipolar disorder
J. Söderlund, S.K. Olsson, M. Samuelsson, L. Walther-Jallow, C. Johansson, S. Erhardt, M. Landén, G. Engberg

Complementary diffusion tensor imaging study of the corpus callosum in patients with first-episode and chronic schizophrenia
X. Kong, X. Ouyang, H. Tao, H. Liu, L. Li, J. Zhao, Z. Xue, F. Wang, S. Jiang, B. Shan, Z. Liu

Reduced prepulse inhibition in adolescents at risk for psychosis: a 2-year follow-up study
T. Ziermans, P. Schothorst, M. Magnée, H. van Engeland, C. Kemner

Psychopharmacology for the Clinician

Identification and management of cryptic bipolarity in patients with TRD
V. Sharma

CCNP News and Views

In memoriam: Alan Boulton, 1936–2010
G.B. Baker, A. Holt, D.D. Mousseau

January 2012

J Psychiatry Neurosci 2012;37(1)


Psychiatry’s age of enlightenment: optogenetics and the discovery of novel targets for the treatment of psychiatric disorders
M.M. Sidor

Review Papers

A role for Akt and glycogen synthase kinase-3 as integrators of dopamine and serotonin neurotransmission in mental health
J.-M. Beaulieu

Does the salience network play a cardinal role in psychosis? An emerging hypothesis of insular dysfunction
L. Palaniyappan, P.F. Liddle

Research Papers

Abnormal hippocampal activation in patients with extensive history of major depression: an fMRI study
A.M.B. Milne, G.M. MacQueen, G.B.C. Hall

Effects of early-life adversity on white matter diffusivity changes in patients at risk for major depression
T. Frodl, A. Carballedo, A.J. Fagan, D. Lisiecka, Y. Ferguson, J.F. Meaney

Parent-of-origin effects of FAS and PDLIM1 in attention-deficit/hyperactivity disorder
K.-S. Wang, X. Liu, Q. Zhang, N. Aragam, Y. Pan

Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls
M. Holtze, P. Saetre, G. Engberg, L. Schwieler, T. Werge, O.A. Andreassen, H. Hall, L. Terenius, I. Agartz, E.G. Jönsson, M. Schalling, S. Erhardt


2011 Reviewers

Psychopharmacology for the Clinician

Adverse events associated with switching antipsychotics
J. Su, A.M. Barr, R.M. Procyshyn

March 2012

J Psychiatry Neurosci 2012;37(2)


Abnormal synaptic pruning in schizophrenia: Urban myth or reality?
P. Boksa

Research Papers

Stress response in postpartum women with and without obsessive–compulsive symptoms: an fMRI study
C. Lord, M. Steiner, C.N. Soares, C.L. Carew, G.B. Hall

Working memory processing of traumatic material in women with posttraumatic stress disorder
L. Landré, C. Destrieux, F. Andersson, L. Barantin, Y. Quidé, G. Tapia, N. Jaafari, D. Clarys, P. Gaillard, M. Isingrini, W. El-Hage

Event-related potentials and changes of brain rhythm oscillations during working memory activation in patients with first-episode psychosis
P. Missonnier, F.R. Herrmann, A. Zanello, M. Badan Bâ, L. Curtis, D.Canovas, F. Chantraine, J. Richiardi, P. Giannakopoulos, M.C.G. Merlo

Voxel-wise meta-analysis of fMRI studies in patients at clinical high risk for psychosis
P. Fusar-Poli

Long-term administration of the dopamine D3/2 receptor agonist pramipexole increases dopamine and serotonin neurotransmission in the male rat forebrain
O. Chernoloz, M. El Mansari, P. Blier

Is the Gly82Ser polymorphism in the RAGE gene relevant to schizophrenia and the personality trait psychoticism?
P. Suchankova, J. Klang, C. Cavanna, G. Holm, S. Nilsson, E.G. Jönsson, A. Ekman

Differential association between the norepinephrine transporter gene and ADHD: role of sex and subtype
S.M. Sengupta, N. Grizenko, G.A. Thakur, J. Bellingham, R. DeGuzman, S. Robinson, M. TerStepanian, A. Poloskia, S.M. Shaheen, M.-E. Fortier, Z. Choudhry, R. Joober

Psychopharmacology for the Clinician

Managing pathologic aggression in people with psychotic disorders
D. Bourget, A. Labelle

May 2012

J Psychiatry Neurosci 2012;37(3)


Publication bias: What are the challenges and can they be overcome?
R. Joober, N. Schmitz, L. Annable, P. Boksa

Review Paper

Systematic review of the neural basis of social cognition in patients with mood disorders
A.M. Cusi, A. Nazarov, K. Holshausen, G.M. MacQueen, M.C. McKinnon 

Research Papers

Mapping vulnerability to bipolar disorder: a systematic review and meta-analysis of neuroimaging studies
P. Fusar-Poli, O. Howes, A. Bechdolf, S. Borgwardt

Large positive effect of lithium on prefrontal cortex N-acetylaspartate in patients with bipolar disorder: 2-centre study
T. Hajek, M. Bauer, A. Pfennig, J. Cullis, J. Ploch, C. O’Donovan, G. Bohner, R. Klingebiel, L.T. Young, G.M. MacQueen, M. Alda

Evidence for fractional anisotropy and mean diffusivity white matter abnormalities in the internal capsule and cingulum in patients with obsessive–compulsive disorder
C. Lochner, J.-P. Fouché, S. du Plessis, B. Spottiswoode, S. Seedat, N. Fineberg, S.R. Chamberlain, D.J. Stein

Psychopharmacology for the Clinician

Will lithium damage my kidneys?
T.J. Raedler

May 2011

J Psychiatry Neurosci 2011;36(3)


The 1000 Genomes Project: deep genomic sequencing waiting for deep psychiatric phenotyping
R. Joober

Review Paper

Atypical scanpaths in schizophrenia: Evidence of a trait- or state-dependent phenomenon?
S.A. Beedie, D.M. St. Clair, P.J. Benson

Research Papers

Effect of executive functioning, decision-making and self-reported impulsivity on the treatment outcome of pathologic gambling
E.M. Álvarez-Moya, C. Ochoa, S. Jiménez-Murcia, M.N. Aymamí, M. Gómez-Peña, F. Fernández-Aranda, J. Santamaría, L. Moragas, F. Bove, J.M. Menchón

Structural alterations in lateral prefrontal, parietal and posterior midline regions of men with chronic posttraumatic stress disorder
C. Eckart, C. Stoppel, J. Kaufmann, C. Tempelmann, H. Hinrichs, T. Elbert, H.-J. Heinze, I.-T. Kolassa

Depression in patients with Huntington disease correlates with alterations of the brain stem raphe depicted by transcranial sonography
C. Krogias, K. Strassburger, J. Eyding, R. Gold, C. Norra, G. Juckel, C. Saft, D. Ninphius

Decreased BDNF, trkB-TK+ and GAD67 mRNA expression in the hippocampus of individuals with schizophrenia and mood disorders
M. Thompson Ray, C.S. Weickert, E. Wyatt, M.J. Webster

CCNP News and Views

2011 award winners

Psychopharmacology for the Clinician

Treatment of ADHD in patients unresponsive to methylphenidate
L. Hechtman

July 2011

J Psychiatry Neurosci 2011;36(4)


My 21 years with the Journal of Psychiatry and Neuroscience, with observations on editors, editorial boards, authors and reviewers
S.N. Young

Review Paper

Contribution of nonprimate animal models in understanding the etiology of schizophrenia
N.L. Lazar, R.W.J. Neufeld, D.P. Cain

Research Papers

White matter alterations related to P300 abnormalities in individuals at high risk for psychosis: an MRI–EEG study
P. Fusar-Poli, N. Crossley, J. Woolley, F. Carletti, R. Perez-Iglesias, M. Broome, L. Johns, P. Tabraham, E. Bramon, P. McGuire

Topiramate diminishes fear memory consolidation and extinguishes conditioned fear in rats
P.A. Schmidt do Prado-Lima, M.F. Perrenoud, C.H. Kristensen, M. Cammarota, I. Izquierdo

Structural brain abnormalities common to posttraumatic stressdisorder and depression
M.C.W. Kroes, M.D. Rugg, M.G. Whalley, C.R. Brewin

Psychopharmacology for the Clinician

Managing anxiety and depressive symptoms in adults with autism-spectrum disorders
K. Boyd, M. Woodbury-Smith, P. Szatmari

September 2011

J Psychiatry Neurosci 2011;36(5)


Inflaming depression
H. Anisman

Review Paper

Role of netrin-1 in the organization and function of the mesocorticolimbic dopamine system
C. Flores

Research Papers

Differential brain glucose metabolic patterns in antipsychotic-naive first-episode schizophrenia with and without auditory verbal hallucinations
G. Horga, E. Parellada, F. Lomeña, E. Fernández-Egea, A. Mané, M. Font, C. Falcón, A.B. Konova, J. Pavia, D. Ros, M. Bernardo

Fluoxetine affects GluK2 editing, glutamate-evoked Ca2+ influx and extracellular signal-regulated kinase phosphorylation in mouse astrocytes
B. Li, S. Zhang, H. Zhang, L. Hertz, L. Peng

Psychopharmacology for the Clinician

Bright light for nonseasonal depression?
S.N. Young

November 2011

J Psychiatry Neurosci 2011;36(6)


What is a functional genetic polymorphism? Defining classes of functionality
P.R. Albert

Research Papers

Dysconnectivity of multiple resting-state networks in patients with schizophrenia who have persistent auditory verbal hallucinations
N.D. Wolf, F. Sambataro, N. Vasic, K. Frasch, M. Schmid, C. Schönfeldt-Lecuona, P.A. Thomann, R.C. Wolf

Monoamine oxidase A inhibitor occupancy during treatment of major depressive episodes with moclobemide or St. John’s wort: an [11C]-harmine PET study
J. Sacher, S. Houle, J. Parkes, P. Rusjan, S. Sagrati, A.A. Wilson, J.H. Meyer

Emotion recognition and experience in Huntington disease: a voxel-based morphometry study
R. Ille, A. Schäfer, W. Scharmüller, C. Enzinger, H. Schöggl, H.-P. Kapfhammer, A. Schienle

Combined analysis of grey matter voxel-based morphometry and white matter tract-based spatial statistics in late-life bipolar disorder
S. Haller, A. Xekardaki, C. Delaloye, A. Canuto, K.O. Lövblad, G. Gold, P. Giannakopoulos

Aberrant connectivity of resting-state networks in borderline personality disorder
R.C. Wolf, F. Sambataro, N. Vasic, M. Schmid, P.A. Thomann, S.D. Bienentreu, N.D. Wolf

Can Asperger syndrome be distinguished from autism? An anatomic likelihood meta-analysis of MRI studies
K.K. Yu, C. Cheung, S.E. Chua, G.M. McAlonan

Psychopharmacology for the Clinician

Discontinuation of lithium because of side effects
T. Hajek, M. Alda, P. Grof

July 2012

J Psychiatry Neurosci 2012;37(4)


Illness comorbidity as a biomarker?
H. Anisman, S. Hayley

Research Papers

Behavioural therapy based on distraction alleviates impaired fear extinction in male serotonin transporter knockout rats
L.J.P. Nonkes, M. de Pooter, J.R. Homberg

Brain functional connectivity during induced sadness in patients with obsessive–compulsive disorder
L.F. Fontenelle, B.J. Harrison, J. Pujol, C.G. Davey, A. Fornito, E. Bora, C. Pantelis, M. Yücel

Altered resting-state amygdala functional connectivity in men with posttraumatic stress disorder
R.K. Sripada, A.P. King, S.N. Garfinkel, X. Wang, C.S. Sripada, R.C. Welsh, I. Liberzon

Decreased cognitive control in response to negative information in patients with remitted depression: an event-related potential study
M.-A. Vanderhasselt, R. De Raedt, D.G. Dillon, S.J. Dutra, N. Brooks, D.A. Pizzagalli

Nonlinear analysis of electroencephalogram at rest and during cognitive tasks in patients with schizophrenia
E. Carlino, M. Sigaudo, A. Pollo, F. Benedetti, T. Mongini, F. Castagna, S. Vighetti, P. Rocca

Ionotropic glutamate receptor mRNA editing in the prefrontal cortex: no alterations in schizophrenia or bipolar disorder
R. Lyddon, S. Navarrett, S. Dracheva

Association between the NMDA glutamate receptor GRIN2B gene and obsessive–compulsive disorder
P. Alonso, M. Gratacós, C. Segalàs, G. Escaramís, E. Real, M. Bayés, J. Labad, C. López-Solà, X. Estivill, J.M. Menchón

Psychopharmacology for the Clinician

Prophylaxis and treatment of bipolar disorder in older adults
C.L. Allan, K.P. Ebmeier

September 2012

J Psychiatry Neurosci 2012;37(5)


Drugs for kids: Good or bad?
P.R. Albert

Research Papers

Schizophrenia with preserved insight is associated with increased perfusion of the precuneus
C. Faget-Agius, L. Boyer, R. Padovani, R. Richieri, O. Mundler, C. Lançon, E. Guedj

Magnetic resonance imaging correlates of first-episode psychosis in young adult male patients: combined analysis of grey and white matter
A. Ruef, L. Curtis, G. Moy, S. Bessero, M. Badan Bâ, F. Lazeyras, K.-O. Lövblad, S. Haller, A. Malafosse, P. Giannakopoulos, M. Merlo

Neurophysiological biomarkers support bipolar-spectrum disorders within psychosis cluster
M. Kaur, R.A. Battisti, J. Lagopoulos, P.B. Ward, I.B. Hickie, D.F. Hermens

Food motivation circuitry hypoactivation related to hedonic and nonhedonic aspects of hunger and satiety in women with active anorexia nervosa and weight-restored women with anorexia nervosa
L.M. Holsen, E.A. Lawson, J. Blum, E. Ko, N. Makris, P.K. Fazeli, A. Klibanski, J.M. Goldstein

Smaller hippocampal volumes in patients with bipolar disorder are masked by exposure to lithium: a meta-analysis
T. Hajek, M. Kopecek, C. Höschl, M. Alda

Psychopharmacology for the Clinician

Antidepressant medication to treat anxiety in patients with bipolar disorder
S. Hassel, G. MacQueen