November 2012

J Psychiatry Neurosci 2012;37(6)


Loose ends of psychiatric research
M. Alda, T. Hajek

Review Paper

Inhibition of the cortex using transcranial magnetic stimulation in psychiatric populations: current and future directions
N. Radhu, L.N. Ravindran, A.J. Levinson, Z.J. Daskalakis

Research Papers

Reduced neural activity of the prefrontal cognitive control circuitry during response inhibition to negative words in people with schizophrenia
A. Vercammen, R. Morris, M.J. Green, R. Lenroot, J. Kulkarni, V.J. Carr, C.S. Weickert, T.W. Weickert

Comparison of brain volume abnormalities between ADHD and conduct disorder in adolescence
M.C. Stevens, E. Haney-Caron

Aberrant cortical gyrification in schizophrenia: a surface-based morphometry study
L. Palaniyappan, P.F. Liddle

Differential effects of 3 classes of antidiabetic drugs on olanzapine-induced glucose dysregulation and insulin resistance in female rats
H.N. Boyda, R.M. Procyshyn, L. Tse, E. Hawkes, C.H. Jin, C.C.Y. Pang, W.G. Honer, A.M. Barr

Psychopharmacology for the Clinician

Management of comorbid Tourette syndrome and attention-deficit/ hyperactivity disorder: Are psychostimulants an option?
T. Pringsheim

January 2013

J Psychiatry Neurosci 2013;38(1)


What does it mean to have enough evidence?
G. MacQueen

Review Paper

Glutamate system, amyloid β peptides and tau protein: functional interrelationships and relevance to Alzheimer disease pathology
T.J. Revett, G.B. Baker, J. Jhamandas, S. Kar

Research Papers

Dexamphetamine selectively increases 40 Hz auditory steady state response power to target and nontarget stimuli in healthy humans
M.A. Albrecht, G. Price, J. Lee, R. Iyyalol, M.T. Martin-Iverson

Structural brain correlates of sensorimotor gating in antipsychotic-naive men with first-episode schizophrenia
T.B. Hammer, B. Oranje, A. Skimminge, B. Aggernaes, B.H. Ebdrup, B. Glenthøj, W. Baaré

Impaired interhemispheric connectivity in medication-naive patients with major depressive disorder
K. Xu, W. Jiang, L. Ren, X. Ouyang, Y. Jiang, F. Wu, L. Kong, F. Womer, Z. Liu, H.P. Blumberg, Y. Tang, F. Wang

Is depression a disconnection syndrome? Meta-analysis of diffusion tensor imaging studies in patients with MDD
Y. Liao, X. Huang, Q. Wu, C. Yang, W. Kuang, M. Du, S. Lui, Q. Yue, R.C.K. Chan, G.J. Kemp, Q. Gong

Functional network connectivity of pain-related resting state networks in somatoform pain disorder: an exploratory fMRI study
A. Otti, H. Guendel, P. Henningsen, C. Zimmer, A.M. Wohlschlaeger, M. Noll-Hussong

Psychopharmacology for the Clinician

SSRIs in a case of selective mutism
K. Manassis, D. Avery


Thank you to those who reviewed submissions to the journal in 2012

March 2013

J Psychiatry Neurosci 2013;38(2)


A way forward for research on biomarkers for psychiatric disorders
P. Boksa


Single treatments that have lasting effects: some thoughts on the antidepressant effects of ketamine and botulinum toxin and the anxiolytic effect of psilocybin
S.N. Young

Review Paper

Overview of potential procedural and participant- related confounds for neuroimaging of the resting state
N.W. Duncan, G. Northoff

Research Papers

Dopamine D2 and D3 binding in people at clinical high risk for schizophrenia, antipsychotic-naive patients and healthy controls while performing a cognitive task
I. Suridjan, P. Rusjan, J. Addington, A.A. Wilson, S. Houle, R. Mizrahi

Hippocampal abnormalities of glutamate/glutamine, N-acetylaspartate and choline in patients with depression are related to past illness burden
J. de Diego-Adeliño, M.J. Portella, B. Gómez-Ansón, O. López-Moruelo, M. Serra-Blasco, Y. Vives, D. Puigdemont, R. Pérez-Egea, E. Álvarez, V. Pérez

Recruitment of the left hemispheric emotional attention neural network in risk for and protection from depression
D.M. Lisiecka, A. Carballedo, A.J. Fagan, Y. Ferguson, J. Meaney, T. Frodl

Morphometric differences in central stress-regulating structures between women with and without borderline personality disorder
A. Kuhlmann, K. Bertsch, I. Schmidinger, P.A. Thomann, S.C. Herpertz

Psychopharmacology for the Clinician

Antidepressants and QTc prolongation
R.W. Lam

March 2014

J Psychiatry Neurosci 2014;39(2)


Clearing the smoke: What do we know about adolescent cannabis use and schizophrenia?
M.N. Hill

Research Papers

Characterization of major depressive disorder using a multiparametric classification approach based on high resolution structural images
L. Qiu, X. Huang, J. Zhang, Y. Wang, W. Kuang, J. Li, X. Wang, L. Wang, X. Yang, S. Lui, A. Mechelli, Q. Gong

Abnormal synchrony of resting state networks in premanifest and symptomatic Huntington disease: the IMAGE-HD study
G.R. Poudel, G.F. Egan, A. Churchyard, P. Chua, J.C. Stout, N. Georgiou-Karistianis

Neural correlates of recognition memory of social information in people with schizophrenia
P.-O. Harvey, M. Lepage

Effects of dopaminergic modulation on automatic semantic priming: a double-blind study
C. Andreou, K. Veith, V.P. Bozikas, T.M. Lincoln, S. Moritz

Impaired musical ability in people with schizophrenia
S. Hatada, K. Sawada, M. Akamatsu, E. Doi, M. Minese, M. Yamashita, A.E. Thornton, W.G. Honer, S. Inoue

Smaller stress-sensitive hippocampal subfields in women with borderline personality disorder without posttraumatic stress disorder
E. Bøen, L.T. Westlye, T. Elvsåshagen, B. Hummelen, P.K. Hol, B. Boye, S. Andersson, S. Karterud, U.F. Malt

Cognitive impairment with and without depression history: an analysis of white matter microstructure
S.L. Duffy, M. Paradise, I.B. Hickie, S.J.G. Lewis, S.L. Naismith, J. Lagopoulos

Psychopharmacology for the Clinician

Assessment of adult attention-deficit/ hyperactivity disorder
V. Bhat, J. Paris

May 2013

J Psychiatry Neurosci 2013;38(3)


On the simple and the complex in psychiatry, with reference to DSM 5 and Research Domain Criteria
R. Joober

Review Paper

Cytochrome P450–mediated drug metabolism in the brain
S. Miksys, R.F. Tyndale

Research Papers

Emotional modulation of motor response inhibition in women with borderline personality disorder: an fMRI study
G.A. Jacob, K. Zvonik, S. Kamphausen, A. Sebastian, S. Maier, A. Philipsen, L. Tebartz van Elst, K. Lieb, O. Tüscher

Functional neural correlates of emotional expression processing deficits in behavioural variant frontotemporal dementia
K. Virani, S. Jesso, A. Kertesz, D. Mitchell, E. Finger

Glutamine deficiency in the prefrontal cortex increases depressive-like behaviours in male mice
Y. Lee, H. Son, G. Kim, S. Kim, D.H. Lee, G.S. Roh, S.S. Kang, G.J. Cho, W.S. Choi, H.J. Kim

Protocadherin α (PCDHA) as a novel susceptibility gene for autism
A. Anitha, I. Thanseem, K. Nakamura, K. Yamada, Y. Iwayama, T. Toyota, Y. Iwata, K. Suzuki, T. Sugiyama, M. Tsujii, T. Yoshikawa, N. Mori

CCNP News and Views

In memoriam: Claude de Montigny, 1945–2012

Canadian College of Neuropsychopharmacology 2013 award winners

Psychopharmacology for the Clinician

Diagnosis and management of periodic catatonia
W.M. Hervey, J.T. Stewart, G. Catalano

January 2014

J Psychiatry Neurosci 2014;39(1)


Light up your life: Optogenetics for depression?
P.R. Albert

Review Paper

Unveiling the role of melatonin MT2 receptors in sleep, anxiety and other neuropsychiatric diseases: a novel target in psychopharmacology
S. Comai, G. Gobbi

Research Papers

Abnormal interhemispheric connectivity in male psychopathic offenders
S.S. Hoppenbrouwers, D.R. De Jesus, Y. Sun, T. Stirpe, D. Hofman, J. McMaster, G. Hughes, Z.J. Daskalakis, D.J.L.G. Schutter

Association of a risk allele of ANK3 with cognitive performance and cortical thickness in patients with first-episode psychosis
C. Cassidy, L. Buchy, M. Bodnar, J. Dell’Elce, Z. Choudhry, F. Fathalli, S. Sengupta, R. Fox, A. Malla, M. Lepage, S. Iyer, R. Joober

Levomilnacipran ER 40 mg and 80 mg in patients with major depressive disorder: a phase III, randomized, double-blind, fixed-dose, placebo-controlled study
D. Bakish, A. Bose, C. Gommoll, C. Chen, R. Nunez, W.M. Greenberg, M. Liebowitz, A. Khan

Effect of childhood maltreatment on brain structure in adult patients with major depressive disorder and healthy participants
A. Chaney, A. Carballedo, F. Amico, A. Fagan, N. Skokauskas, J. Meaney, T. Frodl

Cerebellar motor learning deficits in medicated and medication-free men with recent-onset schizophrenia
M. Coesmans, C.H. Röder, A.E. Smit, S.K.E. Koekkoek, C.I. De Zeeuw, M.A. Frens, J.N. van der Geest


Possible role of more positive social behaviour in the clinical effect of antidepressant drugs
S.N. Young, D.S. Moskowitz, M. aan het Rot


2013 Reviewers

Psychopharmacology for the Clinician

Off-label antipsychotic use and tardive dyskinesia in at-risk populations: new drugs with old side effects
G. Remington, M. Hahn

July 2013

J Psychiatry Neurosci 2013;38(4)


Are addictions diseases or choices?
M. Leyton

Review Paper

Propranolol’s effects on the consolidation and reconsolidation of long-term emotional memory in healthy participants: a meta-analysis
M.H. Lonergan, L.A. Olivera-Figueroa, R.K. Pitman, A. Brunet

Research Papers

RETRACTED, October 7, 2015: Altered affective, executive and sensorimotor resting state networks in patients with pediatric mania
M. Wu, L.H. Lu, A.M. Passarotti, E. Wegbreit, J. Fitzgerald, M.N. Pavuluri

Catechol-O-methyltransferase genotype modifies executive functioning and prefrontal functional connectivity in women with anorexia nervosa
A. Favaro, M. Clementi, R. Manara, R. Bosello, M. Forzan, A. Bruson, E. Tenconi, D. Degortes, F. Titton, F. Di Salle, P. Santonastaso

Mood-congruent amygdala responses to subliminally presented facial expressions in major depression: associations with anhedonia
A. Stuhrmann, K. Dohm, H. Kugel, P. Zwanzger, R. Redlich, D. Grotegerd, A.V. Rauch, V. Arolt, W. Heindel, T. Suslow, P. Zwitserlood, U. Dannlowski

Short-term social isolation induces depressive-like behaviour and reinstates the retrieval of an aversive task: Mood-congruent memory in male mice?
A.L. Takatsu-Coleman, C.L. Patti, K.A. Zanin, A. Zager, R.C. Carvalho, A.R. Borçoi, L.M.B. Ceccon, L.F. Berro, S. Tufik, M.L. Andersen, R. Frussa-Filho

2011 CCNP Heinz Lehman Award paper
Searching for an endogenous anti-Alzheimer molecule: identifying small molecules in the brain that slow Alzheimer disease progression by inhibition of β-amyloid aggregation
A.R. Meek, G.A. Simms, D.F. Weaver

Gene expression deficits in pontine locus coeruleus astrocytes in men with major depressive disorder
M.J. Chandley, K. Szebeni, A. Szebeni, J. Crawford, C.A. Stockmeier, G. Turecki, J.J. Miguel-Hidalgo, G.A. Ordway

Reversal deficits in individuals with psychopathy in explicit but not implicit learning conditions
I.A. Brazil, J.H.R. Maes, I. Scheper, B.H. Bulten, R.P.C. Kessels, R.J. Verkes, E.R.A. de Bruijn

Decreased cerebrospinal fluid secretogranin II concentrations in severe forms of bipolar disorder
J. Jakobsson, M. Stridsberg, H. Zetterberg, K. Blennow, C-J Ekman; A.G.M. Johansson, C. Sellgren, M. Landén

Letters to the Editor

Escitalopram and QTc prolongation
M. Hasnain, R.H. Howland, W.V.R. Vieweg

Author response
R.W. Lam

Psychopharmacology for the Clinician

Management of clozapine-induced fever: a case of continued therapy throughout fever
N. Martin, R. Williams

November 2013

J Psychiatry Neurosci 2013;38(6)


Personalized psychiatry: many questions, fewer answers
M. Alda

Review Paper

COMT, neuropsychological function and brain structure in schizophrenia: a systematic review and neurobiological interpretation
E. Ira, M. Zanoni, M. Ruggeri, P. Dazzan, S. Tosato

Research Papers

Brain structural plasticity in survivors of a major earthquake
S. Lui, L. Chen, L. Yao, Y. Xiao, Q.-Z. Wu, J.-R. Zhang, X.-Q. Huang, W. Zhang, Y.-Q. Wang, H.-F. Chen, R.C.K. Chan, J.A. Sweeney, Q.Y. Gong

Dopamine and light: dissecting effects on mood and motivational states in women with subsyndromal seasonal affective disorder
E.I. Cawley, S. Park, M. aan het Rot, K. Sancton, C. Benkelfat, S.N. Young, D.B. Boivin, M. Leyton

Atypical vertical sound localization and sound-onset sensitivity in people with autism spectrum disorders
E. Visser, M.P. Zwiers, C.C. Kan, L. Hoekstra, A.J. van Opstal, J.K. Buitelaar

Impaired fixation to eyes during facial emotion labelling in children with bipolar disorder or severe mood dysregulation
P. Kim, J. Arizpe, B.H. Rosen, V. Razdan, C.T. Haring, S.E. Jenkins, C.M. Deveney, M.A. Brotman, R.J.R. Blair, D.S. Pine, C.I. Baker, E. Leibenluft

Functional connectivity between the amygdala and prefrontal cortex in medication-naive individuals with major depressive disorder
L. Kong, K. Chen, Y. Tang, F. Wu, N. Driesen, F. Womer, G. Fan, L. Ren, W. Jiang, Y. Cao, H.P. Blumberg, K. Xu, F. Wang


Elevated incidence of suicide in people living at altitude, smokers and patients with chronic obstructive pulmonary disease and asthma: possible role of hypoxia causing decreased serotonin synthesis
S.N. Young


Are addictions diseases or choices?

Psychopharmacology for the Clinician

Mixed depression in the postpartum period: diagnostic and treatment issues
V. Sharma

September 2013

J Psychiatry Neurosci 2013;38(5)


Neurotrophic paths in the treatment of depression
S. Hayley, H. Anisman

Review Paper

Acute tryptophan depletion in humans: a review of theoretical, practical and ethical aspects
S.N. Young

Research Papers

Glycine site N-methyl-D-aspartate receptor antagonist 7-CTKA produces rapid antidepressant-like effects in male rats
W.-L. Zhu, S.-J. Wang, M.-M. Liu, H.-S. Shi, R.-X. Zhang, J.-F. Liu, Z.-B. Ding, L. Lu

Eye movements during natural actions in patients with schizophrenia
C. Delerue, M. Hayhoe, M. Boucart

Double-blind optimization of subcallosal cingulate deep brain stimulation for treatment-resistant depression: a pilot study
R. Ramasubbu, S. Anderson, A. Haffenden, S. Chavda, Z.H.T. Kiss

Atypical coupling between posterior regions of the default mode network in attention-deficit/hyperactivity disorder: a pharmaco-magnetoencephalography study
J.D. Franzen, E. Heinrichs-Graham, M.L. White, M.W. Wetzel, N.L. Knott, T.W. Wilson

Inhibition of fear is differentially associated with cycling estrogen levels in women
E.M. Glover, K.B. Mercer, S.D. Norrholm, M. Davis, E. Duncan, B. Bradley, K.J. Ressler, T. Jovanovic

Impaired inhibition of prepotent motor actions in patients with Tourette syndrome
S.A. Wylie, D.O. Claassen, K.E. Kanoff, K.R. Ridderinkhof, W.P.M. van den Wildenberg

Psychopharmacology for the Clinician

Management strategies for SSRIinduced sexual dysfunction
S. J. Rizvi, S.H. Kennedy


Are addictions diseases or choices?

Online Letters to the Editor

Antidepressant effects of botulinum toxin A: scientific rationale
E. Finzi

Author response
S.N. Young